Evidence map›Paper›PMID 35881837›Full record

ArticleDiabetes2022

The Yin and Yang of Modulating β-Cell DNA Damage Response and Functional Mass.

Jason M Spaeth, Sangeeta Dhawan

Abstract readComment
In one paragraph

Article in Diabetes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Jason M SpaethDepartment of Biochemistry and Molecular Biology and Department of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine, Indianapolis, IN.
Sangeeta DhawanDepartment of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA.ORCID 0000-0002-1562-7899

Funding

Translation CoreP30DK097512 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI Carmella Evans-Molina · 2015 to 2026
$17.4M
Renewal of the Human Islet Research Enhancement Center (HIREC) for the Type-1-Diabetes-Focused Human Islet Research Network (HIRN).U24DK104162 · NIDDK · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI John S. Kaddis, Joyce Carol Niland · 2019 to 2026
$12.3M
Human Islet Research Network (HIRN) Coordinating CenterU01DK104162 · NIDDK · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI NILAND, JOYCE CAROL · 2014 to 2018
$6.1M
Regulation of beta-cell homeostasis by DNA methylation and hydroxymethylation.R01DK120523 · NIDDK · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI DHAWAN, SANGEETA · 2019 to 2023
$2.2M
The Pdx1-recruited Swi/Snf chromatin remodeling complex regulates endocrine cell expansion and differentiation in vivoR03DK127129 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI SPAETH, JASON M · 2021 to 2022
$238k
NIDDK NIH HHS P30 DK097512NIDDK NIH HHS R01 DK120523NIDDK NIH HHS R03 DK127129NIDDK NIH HHS U01 DK104162NIDDK NIH HHS U24 DK104162
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA Damage

Identifiers

PMID35881837
PMCPMC9490355

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.