Evidence map›Paper›PMID 35881808›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Bioinspired stretchable molecular composites of 2D-layered materials and tandem repeat proteins.

Mert Vural, Tarek Mazeed, Dong Li, Oguzhan Colak, Reginald F Hamilton, Huajian Gao, Melik C Demirel

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Impact of biomanufacturing protein fibers on achieving sustainable development.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mert VuralCenter for Research on Advanced Fiber Technologies (CRAFT), Department of Engineering Science and Mechanics, Materials Research Institute, Pennsylvania State University, University Park, PA 16802.ORCID 0000-0003-3309-7323
Tarek MazeedCenter for Research on Advanced Fiber Technologies (CRAFT), Department of Engineering Science and Mechanics, Materials Research Institute, Pennsylvania State University, University Park, PA 16802.ORCID 0000-0002-3704-7617
Dong LiCollege of Engineering and Science, Nanyang Technological University, 639798, Singapore.ORCID 0000-0002-4484-8738
Oguzhan ColakCenter for Research on Advanced Fiber Technologies (CRAFT), Department of Engineering Science and Mechanics, Materials Research Institute, Pennsylvania State University, University Park, PA 16802.ORCID 0000-0003-3751-2272
Reginald F HamiltonCenter for Research on Advanced Fiber Technologies (CRAFT), Department of Engineering Science and Mechanics, Materials Research Institute, Pennsylvania State University, University Park, PA 16802.
Huajian GaoCollege of Engineering and Science, Nanyang Technological University, 639798, Singapore.ORCID 0000-0002-8656-846X
Melik C DemirelCenter for Research on Advanced Fiber Technologies (CRAFT), Department of Engineering Science and Mechanics, Materials Research Institute, Pennsylvania State University, University Park, PA 16802.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein based composites, such as nacre and bone, show astounding evolutionary capabilities, including tunable physical properties. Inspired by natural composites, we studied assembly of atomistically thin inorganic sheets with genetically engineered polymeric proteins to achieve mechanically compliant and ultra-tough materials. Although bare inorganic nanosheets are brittle, we designed flexible composites with proteins, which are insensitive to flaws due to critical structural length scale (∼2 nm). These proteins, inspired by squid ring teeth, adhere to inorganic sheets via secondary structures (i.e., β-sheets and α-helices), which is essential for producing high stretchability (59 ± 1% fracture strain) and toughness (54.8 ± 2 MJ/m

Indexed as

Biomimetic MaterialsProteinsGenetic EngineeringNacrePolymersProtein ConformationTandem Repeat SequencesNacrePolymersProteins2D-layered materialsbiomimeticsmechanical propertiestandem repeat proteins

Identifiers

PMID35881808
PMCPMC9351368

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.