Evidence map›Paper›PMID 35881636›Full record

ArticlePloS one2022

Association between retinal sensitivity and the presence of quiescent choroidal neovascularization in pachychoroid diseases.

Rion Ozawa, Keiko Azuma, Yoko Nomura, Hiroshi Murata, Ryo Asaoka, Kohdai Kitamoto, Kohei Ueda, Tatsuya Inoue, Ryo Obata

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Rion OzawaGraduate School of Medicine and Faculty of Medicine, Department of Ophthalmology, The University of Tokyo, Tokyo, Japan.
Keiko AzumaGraduate School of Medicine and Faculty of Medicine, Department of Ophthalmology, The University of Tokyo, Tokyo, Japan.
Yoko NomuraGraduate School of Medicine and Faculty of Medicine, Department of Ophthalmology, The University of Tokyo, Tokyo, Japan.
Hiroshi MurataGraduate School of Medicine and Faculty of Medicine, Department of Ophthalmology, The University of Tokyo, Tokyo, Japan.
Ryo AsaokaDepartment of Ophthalmology, Seirei Hamamatsu General Hospital, Seirei Christopher University, Shizuoka, Japan.
Kohdai KitamotoGraduate School of Medicine and Faculty of Medicine, Department of Ophthalmology, The University of Tokyo, Tokyo, Japan.
Kohei UedaGraduate School of Medicine and Faculty of Medicine, Department of Ophthalmology, The University of Tokyo, Tokyo, Japan.
Tatsuya InoueDepartment of Ophthalmology and Micro-Technology, Yokohama City University School of Medicine, Minami-ku, Yokohama, Kanagawa, Japan.
Ryo ObataGraduate School of Medicine and Faculty of Medicine, Department of Ophthalmology, The University of Tokyo, Tokyo, Japan.ORCID 0000-0002-1762-0797
The University of Tokyo · JPSeirei Christopher University · JPYokohama City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was conducted to examine retinal sensitivity (RS) in eyes with pachychoroid diseases and to analyze its association with the presence or absence of quiescent choroidal neovascularization (CNV), that can be protective against retinal dysfunction or atrophy in other macular diseases such as age-related macular degeneration. A total of 12 eyes of 12 patients aged ≥45 years having the characteristic findings of central serous chorioretinopathy but not presenting any exudative changes were included in this study. Choroidal vascular hyper permeability (CVH) was identified by indocyanine green angiography, and the presence or absence of CNV was evaluated by optical coherence tomography angiography. RS at 68 points was examined by microperimetry. The average RS corresponding to within and outside CVH was compared. The association between the difference in RS and the presence or absence of CNV was also analyzed. CNV was detected in six eyes (50%). In eyes without CNV, the RS within CVH was similar compared with that outside CVH. However, in eyes with CNV, the RS within CVH was significantly decreased compared with that outside CVH. Multiple regression analysis revealed the presence of CNV as an independent factor associated with RS. In eyes with pachychoroid diseases, RS decreased within the CVH area under the coexistence of nonexudative CNV.

Indexed as

Central Serous ChorioretinopathyChoroidal NeovascularizationChoroidFluorescein AngiographyHumansRetrospective StudiesTomography, Optical Coherence

Identifiers

PMID35881636
PMCPMC9321376
OpenAlexW4288039920

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.