ArticlePLoS pathogens2022
Glycine-serine-rich effector PstGSRE4 in Puccinia striiformis f. sp. tritici inhibits the activity of copper zinc superoxide dismutase to modulate immunity in wheat.
Article in PLoS pathogens, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21 citing papers in PubMed, 39 citations in OpenAlex.
- Systematic Identification and Functional Characterisation of Colletotrichum fructicola Effectors During Camellia oleifera Colonisation.Molecular plant pathology · 2026Article
- Plant-Specific PB1 Domain Complex Mediates Poplar Defence and Is Targeted by Rust Fungus Secreted Protein MlpSD1.Molecular plant pathology · 2026Article
- Vacuolar iron transporters mediate resistance to triadimefon in plant pathogenic fungi.Nature communications · 2026Article
- To win the battle: the chloroplast is a key battleground in plant-pathogen interactions.Horticulture research · 2026Article
- Cereal Cyst Nematode Effector HfVAP2 Targets and Stabilizes TaCAT3-A1 to Suppress Immune Responses for Parasitism in Wheat.Journal of agricultural and food chemistry · 2025Article
- Developing a crop- wild-reservoir pathogen system to understand pathogen evolution and emergence.eLife · 2025Article
- Genomics Research on the Road of Studying Biology and Virulence of Cereal Rust Fungi.Molecular plant pathology · 2025Review
- Computational studies reveal structural characterization and novel families of Puccinia striiformis f. sp. tritici effectors.PLoS computational biology · 2025Article
- Targeting effector proteins of plant pathogens as a strategy for durable plant disease resistance.Frontiers in microbiology · 2025Article
- Uncovering the Mechanisms: The Role of Biotrophic Fungi in Activating or Suppressing Plant Defense Responses.Journal of fungi (Basel, Switzerland) · 2024Review
- Molecular Mechanisms of Plant Responses to Copper: From Deficiency to Excess.International journal of molecular sciences · 2024Review
- Application of Multi-Omics Technologies to the Study of Phytochromes in Plants.Antioxidants (Basel, Switzerland) · 2024Review
- Stripe Rust Effector Pst_9302 Inhibits Wheat Immunity to Promote Susceptibility.Plants (Basel, Switzerland) · 2023Article
- The interaction of two Puccinia striiformis f. sp. tritici effectors modulates high-temperature seedling-plant resistance in wheat.Molecular plant pathology · 2023Article
- The Biological Roles ofBiomolecules · 2023Review
- Molecular Mechanisms of the Co-Evolution of Wheat and Rust Pathogens.Plants (Basel, Switzerland) · 2023Review
- Two salivary proteins Sm10 and SmC002 from grain aphidFrontiers in plant science · 2023Article
- Fungal Effectoromics: A World in Constant Evolution.International journal of molecular sciences · 2022Review
- Microbial Effectors: Key Determinants in Plant Health and Disease.Microorganisms · 2022Review
- Current Status and Future Perspectives of Genomics Research in the Rust Fungi.International journal of molecular sciences · 2022Review
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Authors and funding
13 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Puccinia striiformis f. sp. tritici (Pst) secretes an array of specific effector proteins to manipulate host immunity and promote pathogen colonization. In a previous study, we functionally characterized a glycine-serine-rich effector PstGSRE1 with a glycine-serine-rich motif (m9). However, the mechanisms of glycine-serine-rich effectors (GSREs) remain obscure. Here we report a new glycine-serine-rich effector, PstGSRE4, which has no m9-like motif but inhibits the enzyme activity of wheat copper zinc superoxide dismutase TaCZSOD2, which acts as a positive regulator of wheat resistance to Pst. By inhibiting the enzyme activity of TaCZSOD2, PstGSRE4 reduces H2O2 accumulation and HR areas to facilitate Pst infection. These findings provide new insights into the molecular mechanisms of GSREs of rust fungi in regulating plant immunity.
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