Evidence map›Paper›PMID 35881387›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2022

Ocular Pathology of Cerebral Malaria.

Valerie Ann White, Valentina Barrera, Ian James Callum MacCormick

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Valerie Ann WhiteInternational Agency for Research on Cancer, WHO Classification of Tumours Group, Lyon Cedex, France.ORCID 0000-0002-5124-4553
Valentina BarreraTissue & Eye Services R&D, NHS Blood & Transplant, Liverpool, UK.ORCID 0000-0003-0515-5901
Ian James Callum MacCormickCentre for Inflammation Research, University of Edinburgh, Edinburgh, UK. imaccorm@ed.ac.uk.ORCID 0000-0002-8171-0332

Funding

World Health Organization 001
6 · The paper itself

Abstract

Investigation of post-mortem eyes from children with malarial retinopathy has helped to explain the retinal pathology of cerebral malaria, and also demonstrated histological associations between evolving retinal pathogenesis-visible clinically-and similar cerebral features which can only be examined at autopsy. The pathology of malarial retinopathy has been well-described and correlates with brain pathology. Some clinical and pathological features are associated with outcome. This chapter describes the materials and methods needed to study the pathological features of malarial retinopathy. Some are common to histopathology in general, but accurate spatial correlation between retinal features observed in life and their associated pathology in post-mortem specimens requires special techniques.

Indexed as

Malaria, CerebralMalaria, FalciparumRetinal DiseasesChildHumansRetinaHistopathologyMalarial retinopathyOcular pathologyP. falciparumRetinal hemorrhageRetinal vesselsSequestration

Identifiers

PMID35881387

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.