Evidence map›Paper›PMID 35881370›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2022

Bridging and Clumping: Investigating Platelet Interactions with P. falciparum-Infected Red Blood Cells and Endothelial Cells in Cerebral Malaria.

Samuel Crocodile Wassmer, Georges Emile Raymond Grau, Ian James Callum MacCormick

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 68% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Samuel Crocodile WassmerDepartment of Infection Biology, London School of Hygiene & Tropical Medicine, London, UK.ORCID 0000-0002-6753-3376
Georges Emile Raymond GrauVascular Immunology Unit, School of Medical Sciences, The University of Sydney, Camperdown, NSW, Australia.ORCID 0000-0002-0442-0462
Ian James Callum MacCormickCentre for Inflammation Research, University of Edinburgh, Edinburgh, UK. imaccorm@ed.ac.uk.ORCID 0000-0002-8171-0332
Centre for Inflammation Research · GBLondon School of Hygiene & Tropical Medicine · GBThe University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The methods presented in this chapter describe how to perform ex vivo clumping and in vitro bridging assays in the context of cerebral malaria. Both the protocols are detailed, and emphasis is made on how to prepare platelet suspensions suitable to each technique, including description of specific buffers and reagents to minimize the risk of aggregation while maintaining the platelet properties.

Indexed as

Malaria, CerebralMalaria, FalciparumCell AdhesionEndothelial CellsErythrocytesHumansPlasmodium falciparumAdhesionAdhesion moleculesBridgingCerebral malariaClumpingPlasmodium falciparumPlatelet-poor plasmaPlatelet-rich plasma

Identifiers

PMID35881370
OpenAlexW4288062091

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.