ReviewBrain structure & function2022
Mapping correlated neurological deficits after stroke to distributed brain networks.
Review in Brain structure & function, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 44 citations in OpenAlex.
- Review
- Longitudinal Degeneration of Microstructural and Structural Connectivity Patterns Following Stroke.Stroke · 2026Article
- Functional Connectome Predicts Cognition and Links White Matter Hyperintensity Burden to Cognitive Impairment Across the Vascular Cognitive Impairment Continuum.Brain sciences · 2026Article
- Cortical functional hierarchy disruption following subcortical stroke.BMC medicine · 2026Article
- Visual agnosia in the era of behavioral and neural investigations.Neuropsychologia · 2026Review
- Non-invasive brain stimulation: current and future applications in neurology.Nature reviews. Neurology · 2025Review
- Functional network collapse in neurodegenerative disease.Nature communications · 2025Article
- Reorganized Functional Networks Underlie Working Memory Deficits After Right-Hemispheric Stroke.The European journal of neuroscience · 2025Article
- Understanding the mind-brain relationship through focal neurodegenerative pathology.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Review
- Spatio-Temporal Signatures of Cognitive Function After Pediatric Arterial Ischemic Stroke-A Pilot Study.Human brain mapping · 2025Article
- Evoked slow oscillations and dynamic network reorganization after stroke.Brain communications · 2025Article
- Development of evaluation index system for functional ability of older patients with stroke based on healthy aging: a modified Delphi study.Frontiers in public health · 2025Article
- Latent dimension linking functional connectivity with post-stroke deficits across multiple domains.Brain communications · 2025Article
- Lesion-network mapping in task-dependent frequencies uncovers remote consequences of focal damage.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Recovery of Verbal Working Memory Depends on Left Hemisphere White Matter Tracts.Neurobiology of language (Cambridge, Mass.) · 2025Article
- Article
- Structural brain networks correlating with poststroke cognition.Human brain mapping · 2024Observational
- Assessing the Role of Serum Prealbumin in Prognostic Studies of Stroke: Reflections on Existing Research Methods [Letter].Clinical epidemiology · 2024Article
- Generative whole-brain dynamics models from healthy subjects predict functional alterations in stroke at the level of individual patients.Brain communications · 2024Article
- Normative connectome-based analysis of sensorimotor deficits in acute subcortical stroke.Frontiers in neuroscience · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Understanding the relationships between brain organization and behavior is a central goal of neuroscience. Traditional teaching emphasizes that the human cerebrum includes many distinct areas for which damage or dysfunction would lead to a unique and specific behavioral syndrome. This teaching implies that brain areas correspond to encapsulated modules that are specialized for specific cognitive operations. However, empirically, local damage from stroke more often produces one of a small number of clusters of deficits and disrupts brain-wide connectivity in a small number of predictable ways (relative to the vast complexity of behavior and brain connectivity). Behaviors that involve shared operations show correlated deficits following a stroke, consistent with a low-dimensional behavioral space. Because of the networked organization of the brain, local damage from a stroke can result in widespread functional abnormalities, matching the low dimensionality of behavioral deficit. In alignment with this, neurological disease, psychiatric disease, and altered brain states produce behavioral changes that are highly correlated across a range of behaviors. We discuss how known structural and functional network priors in addition to graph theoretical concepts such as modularity and entropy have provided inroads to understanding this more complex relationship between brain and behavior. This model for brain disease has important implications for normal brain-behavior relationships and the treatment of neurological and psychiatric diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.