ArticleeLife2022
Lung evolution in vertebrates and the water-to-land transition.
Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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Who cites it
19 citing papers in PubMed.
- Comparative Transcriptomics Suggests that Breast Secretory Epithelium Reuses Gene Repertoires Conserved Across Vertebrates Beyond Mammals.Genome biology and evolution · 2026Article
- Pulmonary development in Squamata: Insights from embryonic studies using micro-CT.Developmental dynamics : an official publication of the American Association of Anatomists · 2026Article
- Evolutionary Integration and Glucocorticoid Regulation of the Respiratory System: Structure, Function, and Homeostatic Adaptation.Medical sciences (Basel, Switzerland) · 2026Review
- A dual respiratory and auditory function for the coelacanth lung.Communications biology · 2026Article
- Gut microbiome shifts during frog development parallel host-association patterns across vertebrate lineages.Frontiers in microbiology · 2026Article
- For your eyes too: a new set of images of biological materials from the scientific commissioning of the MOGNO beamline at Sirius.Journal of synchrotron radiation · 2026Article
- Cell Population-resolved Multiomics Atlas of the Developing Lung.American journal of respiratory cell and molecular biology · 2025Article
- Origin and stepwise evolution of vertebrate lungs.Nature ecology & evolution · 2025Article
- Cloned airway basal progenitor cells to repair fibrotic lung through re-epithelialization.Nature communications · 2025Article
- The dynamics of tubulogenesis in development and disease.Development (Cambridge, England) · 2025Review
- Co-option of neck muscles supported the vertebrate water-to-land transition.Nature communications · 2024Article
- Pulmonary arteries in coelacanths shed light on the vasculature evolution of air-breathing organs in vertebrates.Scientific reports · 2024Article
- The Soft Palate Enables Extreme Feeding and Explosive Breathing in the Fin Whale (Integrative organismal biology (Oxford, England) · 2024Article
- Using salamanders as model taxa to understand vertebrate feeding constraints during the late Devonian water-to-land transition.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- The evolution of the various structures required for hearing inIBRO neuroscience reports · 2023Article
- Plastic loss of motile cilia in the gills ofEcology and evolution · 2023Article
- Developmental switch from morphological replication to compensatory growth for salamander lung regeneration.Cell proliferation · 2023Article
- Morphogenetic processes in the development and evolution of the arteries of the pharyngeal arches: their relations to congenital cardiovascular malformations.Frontiers in cell and developmental biology · 2023Review
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Authors and funding
13 authors.
Funding
Abstract
A crucial evolutionary change in vertebrate history was the Palaeozoic (Devonian 419-359 million years ago) water-to-land transition, allowed by key morphological and physiological modifications including the acquisition of lungs. Nonetheless, the origin and early evolution of vertebrate lungs remain highly controversial, particularly whether the ancestral state was paired or unpaired. Due to the rarity of fossil soft tissue preservation, lung evolution can only be traced based on the extant phylogenetic bracket. Here we investigate, for the first time, lung morphology in extensive developmental series of key living lunged osteichthyans using synchrotron x-ray microtomography and histology. Our results shed light on the primitive state of vertebrate lungs as unpaired, evolving to be truly paired in the lineage towards the tetrapods. The water-to-land transition confronted profound physiological challenges and paired lungs were decisive for increasing the surface area and the pulmonary compliance and volume, especially during the air-breathing on land.
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