Evidence map›Paper›PMID 35880568›Full record

ArticleActa biochimica et biophysica Sinica2022

SOX5 promotes cell growth and migration through modulating the DNMT1/p21 pathway in bladder cancer.

Longxiang Wu, Zhongqing Yang, Guoyu Dai, Benyi Fan, Junbin Yuan, Yalin Liu, Peihua Liu, Zhenyu Ou

Open access · diamondAbstract read
In one paragraph

Article in Acta biochimica et biophysica Sinica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. T cell senescence induced by DNMT1 deletion mediates cardiac transplant tolerance via altered CDKN1A methylation.Molecular therapy : the journal of the American Society of Gene Therapy · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Longxiang WuDepartment of Urology, Xiangya Hospital, Central South University, Changsha 410008, China.
Zhongqing YangDepartment of Urology, Xiangya Hospital, Central South University, Changsha 410008, China.
Guoyu DaiDepartment of Urology, Xiangya Hospital, Central South University, Changsha 410008, China.
Benyi FanDepartment of Urology, Xiangya Hospital, Central South University, Changsha 410008, China.
Junbin YuanDepartment of Urology, Xiangya Hospital, Central South University, Changsha 410008, China.
Yalin LiuNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, China.
Peihua LiuDepartment of Urology, Xiangya Hospital, Central South University, Changsha 410008, China.
Zhenyu OuDepartment of Urology, Xiangya Hospital, Central South University, Changsha 410008, China.
Central South University · CNXiangya Hospital Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bladder cancer (BC) is one of the most prevalent and life-threatening cancers among the male population worldwide. Sex determining region Y-box protein 5 (SOX5) plays important roles in a variety of human cancers. However, little research has been conducted on the function and underlying mechanism of SOX5 in BC. In the present study, we first reveal the increased expression of SOX5 in BC tissues and

Indexed as

MicroRNAsUrinary Bladder NeoplasmsCell Line, TumorCell ProliferationDNA (Cytosine-5-)-Methyltransferase 1Gene Expression Regulation, NeoplasticHumansMaleSOXD Transcription FactorsDNA (Cytosine-5-)-Methyltransferase 1DNMT1 protein, humanMicroRNAsSOX5 protein, humanSOXD Transcription Factorsbladder cancerDNA methylationDNMT1p21.SOX5

Identifiers

PMID35880568
PMCPMC9909322
OpenAlexW4281687788

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.