Recent trends in studies of biomolecular phase separation.

Chan-Geun Kim, Da-Eun Hwang, Rajeev Kumar, Min Chung, Yu-Gon Eom, Hyunji Kim, Da-Hyun Koo, Jeong-Mo Choi

Abstract readNews

In one paragraph

Article in BMB reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

Crosstalk between protein post-translational modifications and phase separation.Cell communication and signaling : CCS · 2024
Review
Biomolecular Liquid-Liquid Phase Separation for Biotechnology.Biotech (Basel (Switzerland)) · 2023
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chan-Geun KimDepartment of Chemistry, Pusan National University, Busan 46241, Korea.

Da-Eun HwangDepartment of Chemistry, Pusan National University, Busan 46241, Korea.

Rajeev KumarDepartment of Chemistry, Pusan National University, Busan 46241, Korea.

Min ChungDepartment of Chemistry, Pusan National University, Busan 46241, Korea.

Yu-Gon EomDepartment of Chemistry, Pusan National University, Busan 46241, Korea.

Hyunji KimDepartment of Chemistry, Pusan National University, Busan 46241, Korea.

Da-Hyun KooDepartment of Chemistry, Pusan National University, Busan 46241, Korea.

Jeong-Mo ChoiDepartment of Chemistry, Pusan National University, Busan 46241, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biomolecular phase separation has recently attracted broad interest, due to its role in the spatiotemporal compartmentalization of living cells. It governs the formation, regulation, and dissociation of biomolecular condensates, which play multiple roles in vivo, from activating specific biochemical reactions to organizing chromatin. Interestingly, biomolecular phase separation seems to be a mainly passive process, which can be explained by relatively simple physical principles and reproduced in vitro with a minimal set of components. This Mini review focuses on our current understanding of the fundamental principles of biomolecular phase separation and the recent progress in the research on this topic. [BMB Reports 2022; 55(8): 363-369].

Identifiers

PMID35880435

PMCPMC9442351

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.