ArticleActa otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale2022
The clinical significance of direction-fixed mono-positional apogeotropic horizontal nystagmus.
Article in Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 5 citations in OpenAlex.
- Lying Down Nystagmus in Lateral Canal Paroxysmal Positional Vertigo.Audiology research · 2026Article
- Insights Into Responses to Caloric and Head Impulse Stimulation in Lateral Semicircular Canal Benign Paroxysmal Positional Vertigo.Clinical and experimental otorhinolaryngology · 2025Article
- Epley's Influence on Horizontal Canal BPPV Variants.Audiology research · 2025Review
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2 authors at 1 institution in 1 country.
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Abstract
Objective: A mono-positional persistent, direction-fixed apogeotropic nystagmus (MPosApoNy) is very challenging for the neuro-otologist. MPosApoNy can be found in patients suffering from a partially compensated acute unilateral vestibulopathy; with a normal caloric test, one can speculate the presence of "trapped" otolithic debris located close to the ampulla of the horizontal semicircular canal. Methods: Among 957 patients suffering from vertigo and dizziness, we selected 53 cases of MPosApoNy. Results: In 28 patients, caloric test showed a canal paresis on the same side of the MPosApoNy. In the remaining 25 cases, MPosApoNy was the only clinical finding. We hypothesised the presence of horizonal canal lithiasis and patients were treated with a Gufoni manoeuvre, followed by a forced prolonged position. Conclusions: Performing bedside examination in a patient suffering from vertigo, the presence of MPosApoNy may be due to: a) facilitation of a subclinical nystagmus due to the mechanism of apogeotropic reinforcement; b) horizontal canal lithiasis with 'trapped' otoliths close to the ampulla. The disappearance of MPosApoNy following a repositioning manoeuvre or conversion in a typical form of canalolithiasis may represent the best method to confirm this hypothesis.
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