Evidence map›Paper›PMID 35880136›Full record

ReviewEgyptian liver journal2022

COVID-19 and liver diseases.

Maged T Elghannam, Moataz H Hassanien, Yosry A Ameen, Gamal M ELattar, Ahmed A ELRay, Emad A Turky, Mohammed D ELTalkawy

Open access · diamondAbstract readReview
In one paragraph

Review in Egyptian liver journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Observational
  5. Review
  6. Outcomes of COVID-19 among patients with liver disease.World journal of gastroenterology · 2023
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Maged T ElghannamTheodor Bilharz Research Institute, Giza, Egypt.ORCID 0000-0002-3638-5286
Moataz H HassanienTheodor Bilharz Research Institute, Giza, Egypt.ORCID https://orcid.org/0000-0002-4638-0542
Yosry A AmeenTheodor Bilharz Research Institute, Giza, Egypt.ORCID https://orcid.org/0000-0002-3844-1122
Gamal M ELattarTheodor Bilharz Research Institute, Giza, Egypt.ORCID https://orcid.org/0000-0003-3777-7668
Ahmed A ELRayTheodor Bilharz Research Institute, Giza, Egypt.ORCID https://orcid.org/0000-0002-1214-6459
Emad A TurkyTheodor Bilharz Research Institute, Giza, Egypt.ORCID https://orcid.org/0000-0001-7498-6835
Mohammed D ELTalkawyTheodor Bilharz Research Institute, Giza, Egypt.ORCID https://orcid.org/0000-0002-4860-5231
Theodor Bilharz Research Institute · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus causes an outbreak of viral pneumonia that spread throughout the world. Liver injury is becoming more widely recognized as a component of the clinical picture of COVID-19 infection. Hepatitis with serum ALT elevation has been reported in up to half of patients. Patients with CLD were at a higher risk of decompensation with liver failure, hospitalization, and mortality. The percentage of acute liver injury (ALI) varied from 5 to 28%. COVID-19 hinders HCV elimination by 2030. It is recommended to continue treatment of chronic HCV and chronic HBV if already receiving treatment. Consider using antiviral therapy to prevent viral flare-ups in patients with occult or resolved HBV and COVID-19 who are receiving immunosuppressive agents. Patients with AIH do not have an increased risk of adverse outcomes even in high-risk areas. There is an association between MAFLD and disease progression. Patients with any type of cancer are at a higher risk of infection and are more likely to develop more severe clinical outcomes. Most societies advise against immunosuppressant modifications in patients with mild COVID-19, whereas in rare cases such as severe lymphopenia, worsening pneumonia, or bacterial or fungal superinfection, reduction or discontinuation of antiproliferative agents and lymphocyte-depleting therapies has been suggested.

Indexed as

Autoimmune liver diseaseCoronavirusesCOVID-19 vaccinationHepatocellular carcinomaLiver diseasesLiver transplantationSARS-CoV-2

Identifiers

PMID35880136
PMCPMC9301896
OpenAlexW4286111260

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.