Evidence map›Paper›PMID 35880023›Full record

ArticleCell reports methods2022

Methods for culturing adult CNS neurons reveal a CNS conditioning effect.

Erna A van Niekerk, Riki Kawaguchi, Camila Marques de Freria, Kimberly Groeniger, Maria C Marchetto, Sebastian Dupraz, Frank Bradke, Daniel H Geschwind, Fred H Gage, Mark H Tuszynski

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell reports methods, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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  5. Article
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  7. Poly(curcumin-Journal of neural engineering · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Erna A van NiekerkDepartment of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
Riki KawaguchiDepartments of Neurology and Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Camila Marques de FreriaDepartment of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
Kimberly GroenigerDepartment of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
Maria C MarchettoDepartment of Anthropology, University of California, San Diego, La Jolla, CA, USA.
Sebastian DuprazLaboratory of Axon Growth and Regeneration, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Frank BradkeLaboratory of Axon Growth and Regeneration, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Daniel H GeschwindDepartments of Neurology and Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Fred H GageLaboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Mark H TuszynskiDepartment of Neurosciences, University of California, San Diego, La Jolla, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuronal cultures provide a basis for reductionist insights that rely on molecular and pharmacological manipulation. However, the inability to culture mature

Indexed as

Central Nervous System DiseasesNeuronsAxonsBrainCentral Nervous SystemHumansconditioning lesionneural repairprimary adult neuronal culturesregeneration

Identifiers

PMID35880023
PMCPMC9308166

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.