ArticleThe Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology2022
Transcutaneous Tibial Nerve Stimulation as Therapy for Functional Constipation.
Article in The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 9 citations in OpenAlex.
- COMPARING THE EFFECTS OF BIOFEEDBACK AND TRANSCUTANEOUS TIBIAL NERVE STIMULATION, ALONE OR IN COMBINATION, IN WOMEN WITH COEXISTING COMPLAINTS OF DYSSYNERGIC DEFECATION AND STRESS URINARY INCONTINENCE: A RANDOMIZED CONTROLLED TRIAL.Arquivos de gastroenterologia · 2026Trial
- Responsiveness of the Persian version of the patient assessment of constipation quality of life and Wexner constipation scoring system questionnaires in individuals with dyssynergia defecation following physiotherapy intervention.Gastroenterology and hepatology from bed to bench · 2026Article
- Pelvic floor distress inventory 20 and Wexner constipation scoring system responsiveness and minimal clinical importance difference in Persian women with functional constipation.BMC women's health · 2025Article
- Article
- Sit or Squat? Toilet Type Is a Determinant of Diverticulosis Development.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2024Article
- Review
- Transcutaneous Posterior Tibial Nerve Stimulation: An Adjuvant Treatment for Intractable Constipation in Children.Biomedicines · 2024Article
- Translation, cultural adaptation, reliability, and validity of the Persian version of the Constipation Severity Instrument.Gastroenterology and hepatology from bed to bench · 2024Article
- Posterior tibial nerve electrical stimulation in chronic constipation: a systematic review and meta-analysis.Gastroenterology and hepatology from bed to bench · 2024Review
- Noninvasive electrical neuromodulation for gastrointestinal motility disorders.Expert review of gastroenterology & hepatology · 2023Review
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFunctional constipation is a common disorder that is difficult to treat on occasion. Symptoms of this condition can per- sist despite dietary modification, exercise, and medication. Results of neuromodulation with nerve stimulation have been promising in terms of efficiency for treatment-resistant patients. This study aimed to investigate the efficacy of bilateral transcutaneous tibial nerve stimulation as a noninvasive treatment method for functional constipation.
methodsWe evaluated 105 patients with functional constipation diagnosed using the Rome IV criteria. Bilateral transcutaneous elec- trical nerve stimulation was utilized for transcutaneous tibial nerve stimulation for 6 weeks; 3 sessions were conducted every week, with each session lasting for at least 30 minutes. The Constipation Severity Instrument was used before treatment, at the end of 6 weeks, and at 12 weeks (6 weeks after the end of treatment). The effects of transcutaneous tibial nerve stimulation on the time spent in the toilet and the use of softeners were investigated.
resultsOf the 105 patients included in the study, 41 (39%) were male. The mean age was 43.1 (range, 19-64 years). Transcutaneous tibial nerve stimulation was found to reduce the time patients spent in the toilet. The use of softeners decreased from 76.2% to 20% (P < .001). Obstructive defecation (P < .001), colonic inertia (P < .001), pain (P < .001), and Constipation Severity Instrument total score (P < .001) improved after the 6-week treatment period. The treatment effect persisted until the 12th week.
conclusionBilateral transcutaneous tibial nerve stimulation is a noninvasive, easily applicable, and effective treatment for functional constipation, without major adverse effects. Large randomized controlled trials are required so that transcutaneous tibial nerve stimula- tion can be established as an alternative treatment for functional constipation that is resistant to standard care and laxative agents.
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