Evidence map›Paper›PMID 35879869›Full record

ArticleClinical and experimental pediatrics2023

Not breastfeeding and risk of autism spectrum disorders among children: a meta-analysis.

Ensiyeh Jenabi, Saeid Bashirian, Amir Mohammad Salehi, Salman Khazaei

Open access · diamondAbstract read
In one paragraph

Article in Clinical and experimental pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ensiyeh JenabiMother and Child Care Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
Saeid BashirianAutism Spectrum Disorders Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
Amir Mohammad SalehiSchool of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Salman KhazaeiAutism Spectrum Disorders Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
Hamedan University of Medical Sciences · IR

Funding

Hamadan University of Medical Sciences 140011199609
6 · The paper itself

Abstract

backgroundTo our knowledge, this is the first meta-analysis of the association of not breastfeeding and the risk of autism spectrum disorder (ASD) based on observational studies. PURPOSE: This meta-analysis aimed to evaluate of the association of not breastfeeding and the risk of ASD.

methodsThree databases (PubMed, Web of Science, and Scopus) were systematically searched until December 2021. Heterogeneity was determined using the chi-square test and its quantity was measured using the I2 statistic. The Begg line regression test was used to assess publication bias. A random-effects model was used to analyze the data. Seven studies were included in this meta-analysis.

resultsThe total study population included 3,270 individuals. According to the random-effects model, the estimated odds ratio of the risk of ASD associated with not breastfeeding was 1.81 (95% confidence interval, 1.35-2.27; I2=0%).

conclusionThe results of the included studies were homogeneous. Our findings showed that not breastfeeding is a risk factor for ASD. These results suggest the importance of breastfeeding in decreasing the risk of ASD in children.

Indexed as

Autism spectrum disordersBreastfeedingChildMeta-analysis

Identifiers

PMID35879869
PMCPMC9815942
OpenAlexW4285794096

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.