ArticleJournal of biomedical optics2022
Detection of hypoxia by near-infrared spectroscopy and pulse oximetry: a comparative study.
Article in Journal of biomedical optics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Cardiorespiratory Sensors and Their Implications for Out-of-Hospital Cardiac Arrest Detection: A Systematic Review.Annals of biomedical engineering · 2024Pooled it
- Comparative assessment of healthy tissue oxygenation using near-infrared imaging, transcutaneous oxygen measurement, and plethysmography.Scientific reports · 2025Trial
- Cerebral oxygenation and cognitive performance under different acute normobaric hypoxic conditions: a fNIRS study.European journal of applied physiology · 2026Article
- Validation of A Wireless Telemetric Bladder Pressure Monitoring System in Traumatic Thoracic Spinal Cord Injury in Yucatan Minipigs.Journal of neurotrauma · 2026Article
- The Clinical Relevance of Overnight Oximetry in the Diagnosis of Intermittent Desaturations and the Need for Home Oxygen in the Near-Term and Term Infant.Children (Basel, Switzerland) · 2025Review
- The role of cerebral oxygenation in pediatric lower respiratory tract infections based on insights from time domain near infrared spectroscopy tissue oximetry.Scientific reports · 2025Observational
- Physio-fUS: a tissue-motion based method for heart and breathing rate assessment in neurofunctional ultrasound imaging.EBioMedicine · 2025Article
- Comparing NIRS and Pulse Oximetry for Cerebral Oxygen Saturation During Hypoxia Testing.Medical sciences (Basel, Switzerland) · 2024Article
- Review
- Two-Stream Convolutional Neural Networks for Breathing Pattern Classification: Real-Time Monitoring of Respiratory Disease Patients.Bioengineering (Basel, Switzerland) · 2024Article
- Oxygen Sensor-Guided Fine Needle Biopsy Studies of Human Cancer Xenografts in Mice.bioRxiv : the preprint server for biology · 2024Article
- Noninvasive Monitoring Strategies for Bronchopulmonary Dysplasia or Post-Prematurity Respiratory Disease: Current Challenges and Future Prospects.Children (Basel, Switzerland) · 2023Review
- Modification of a Conventional Deep Learning Model to Classify Simulated Breathing Patterns: A Step toward Real-Time Monitoring of Patients with Respiratory Infectious Diseases.Sensors (Basel, Switzerland) · 2023Article
- Evaluation of transcutaneous near-infrared spectroscopy for early detection of cardiac arrest in an animal model.Scientific reports · 2023Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
significancePulse oximetry is widely used in clinical practice to monitor changes in arterial oxygen saturation (SpO2). However, decreases in SpO2 can be delayed relative to the actual clinical event, and near-infrared spectroscopy (NIRS) may detect alterations in oxygenation earlier than pulse oximetry, as shown in previous cerebral oxygenation monitoring studies.
aimWe aim to compare the response of transcutaneous muscle NIRS measures of the tissue saturation index with pulse oximetry SpO2 during hypoxia. APPROACH: Episodes of acute hypoxia were induced in nine anesthetized Yucatan miniature pigs. A standard pulse oximeter was attached to the ear of the animal, and a transcutaneous NIRS sensor was placed on the hind limb muscle. Hypoxia was induced by detaching the ventilator from the animal and reattaching it once the pulse oximeter reported 70% SpO2.
resultsTwenty-four episodes of acute hypoxia were analyzed. Upon the start of hypoxia, the transcutaneous NIRS measures changed in 5.3 ± 0.4 s, whereas the pulse oximetry measures changed in 14.9 ± 1.0 s (p < 0.0001).
conclusionsTranscutaneous muscle NIRS can detect the effects of hypoxia significantly sooner than pulse oximetry in the Yucatan miniature pig. A transcutaneous NIRS sensor may be used as an earlier detector of oxygen saturation changes in the clinical setting than the standard pulse oximeter.
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