Evidence map›Paper›PMID 35879650›Full record

ArticleBMC molecular and cell biology2022

Angiogenic ability of human endothelial cells was decreased following senescence induction with hydrogen peroxide: possible role of vegfr-2/akt-1 signaling pathway.

Nesa Janamo Berenjabad, Vahid Nejati, Jafar Rezaie

Open access · goldAbstract read
In one paragraph

Article in BMC molecular and cell biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Vascular Ageing: Mechanisms, Risk Factors, and Treatment Strategies.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nesa Janamo BerenjabadDepartment of Biology, Urmia University, Urmia, Iran.
Vahid NejatiDepartment of Biology, Urmia University, Urmia, Iran.
Jafar RezaieSolid Tumor Research Center, Cellular and Molecular Medicine Institute, Urmia University of Medical Sciences, Shafa St, Ershad Blvd, P.O. BoX: 1138, Urmia, Postal Code: 57147, Iran. Rezaie.j@umsu.ac.ir.ORCID http://orcid.org/0000-0001-8175-3730
Urmia University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMany attempts are used to discover mechanisms driving impaired angiogenesis in age-related diseases. Angiogenesis is highly regulated by different signaling pathways. Here, we investigated the angiogenesis potential of human endothelial cells (ECs) upon exposure to hydrogen peroxide (H

resultsData showed that the wound healing rate of HUVECs decreased upon incubation with H

conclusionsOur data showed that H

Indexed as

Hydrogen PeroxideMicroRNAsHumansHuman Umbilical Vein Endothelial CellsProto-Oncogene Proteins c-aktSignal TransductionVascular Endothelial Growth Factor Receptor-2AKT1 protein, humanHydrogen PeroxideKDR protein, humanMicroRNAsProto-Oncogene Proteins c-aktVascular Endothelial Growth Factor Receptor-2Age-related diseasesAngiogenesisH2O2HUVECsSenescence

Identifiers

PMID35879650
PMCPMC9310472
OpenAlexW4287307024

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.