ArticleNature medicine2022
Genetic risk score enhances the risk prediction of severe obesity in adult survivors of childhood cancer.
Article in Nature medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 25 citations in OpenAlex.
- Genetic and physiological insights into satiation variability predict responses to obesity treatment.Cell metabolism · 2025Trial
- Body mass index during and early after therapy for pediatric acute lymphoblastic leukemia is associated with obesity in survivors.Haematologica · 2026Article
- Nutritional Assessment of Children and Adolescents with Cancer in Various Resource Settings.Cancers · 2026Review
- Cardiometabolic outcomes after bariatric surgery in adult survivors of childhood cancer: a St Jude Lifetime Cohort report.Journal of the National Cancer Institute · 2026Article
- Predicting the 10-year risk of cardiomyopathy in long-term survivors of childhood cancer.Annals of oncology : official journal of the European Society for Medical Oncology · 2025Article
- Body mass index-related participation limitations in daily life activities among survivors of childhood cancer: a cross-sectional study.BMJ paediatrics open · 2025Article
- The Effect of Parental Weight and Genetics on the Body Mass Index of Very Low Birth Weight Infants as They Reach School Age.Deutsches Arzteblatt international · 2025Observational
- Genetic and epigenetic bases of long-term adverse effects of childhood cancer therapy.Nature reviews. Cancer · 2025Review
- Genetic factors in the pathogenesis of cardio-oncology.Journal of translational medicine · 2024Review
- Aging and cancer.Molecular cancer · 2024Review
- Polygenic risk scores, radiation treatment exposures and subsequent cancer risk in childhood cancer survivors.Nature medicine · 2024Article
- Modifiable Cardiometabolic Risk Factors in Survivors of Childhood Cancer:JACC. CardioOncology · 2024Review
- Stochastic modeling of obesity status in United States adults using Markov Chains: A nationally representative analysis of population health data from 2017-2020.Obesity science & practice · 2023Article
- Surveillance cardiopulmonary exercise testing can risk-stratify childhood cancer survivors: underlying pathophysiology of poor exercise performance and possible room for improvement.Cardio-oncology (London, England) · 2023Article
- Robust Bioinformatics Approaches Result in the First Polygenic Risk Score for BMI in Greek Adults.Journal of personalized medicine · 2023Article
- Genetic risk scores improve prediction of obesity in survivors of childhood cancer.Nature reviews. Endocrinology · 2022Article
- Predicting chronic morbidity in childhood cancer survivors.Nature medicine · 2022Article
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14 authors at 4 institutions in 2 countries.
Funding
Abstract
Adult survivors of childhood cancer have high rates of obesity, which, in combination with the cardiotoxic effects of specific cancer therapies, places them at high risk for cardiovascular morbidity. Here we show the contribution of genetic risk scores (GRSs) to increase prediction of those survivors of childhood cancer who are at risk for severe obesity (body mass index ≥40 kg m
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.