Evidence map›Paper›PMID 35879609›Full record

ArticleNature methods2022

Why it is important to study human-monkey embryonic chimeras in a dish.

Alejandro De Los Angeles, Alan Regenberg, Victoria Mascetti, Nissim Benvenisty, George Church, Hongkui Deng, Juan Carlos Izpisua Belmonte, Weizhi Ji, Julian Koplin, Yuin-Han Loh and 11 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature methods, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 16 institutions in 6 countries.

Alejandro De Los Angeles *Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA. a.delosangeles@alumni.stanford.edu.ORCID http://orcid.org/0000-0001-9433-501X
Alan Regenberg *Johns Hopkins Berman Institute of Bioethics, Johns Hopkins University, Baltimore, MD, USA.ORCID http://orcid.org/0000-0003-0604-9596
Victoria Mascetti *Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA, USA.
Nissim BenvenistyThe Azrieli Center for Stem Cells and Genetic Research, Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.
George ChurchDepartment of Genetics, Harvard Medical School, Boston, MA, USA.
Hongkui DengCollege of Life Sciences and Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China.ORCID http://orcid.org/0000-0003-3045-4428
Juan Carlos Izpisua BelmonteSalk Institute for Biological Studies, La Jolla, CA, USA.ORCID http://orcid.org/0000-0003-0557-8875
Weizhi JiState Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, China.ORCID http://orcid.org/0000-0003-2550-4224
Julian KoplinMelbourne Law School, University of Melbourne, Melbourne, Victoria, Australia.
Yuin-Han LohEpigenetics and Cell Fates Laboratory, A*STAR Institute of Molecular and Cell Biology, Singapore, Singapore.ORCID http://orcid.org/0000-0002-4715-6454
Yuyu NiuState Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, China.
Duanqing PeiLaboratory of Cell Fate Control, School of Life Sciences, Westlake University, Hangzhou, China.
Martin PeraThe Jackson Laboratory, Bar Harbor, ME, USA.ORCID http://orcid.org/0000-0001-6239-0428
Nam PhoDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
Carlos Pinzon-ArteagaDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID http://orcid.org/0000-0002-4906-6751
Mitinori SaitouInstitute for the Advanced Study of Human Biology (ASHBi), Kyoto University, Kyoto, Japan.
Jose C R SilvaGuangzhou Laboratory, Guangzhou International Bio Island, Guangzhou, China.ORCID http://orcid.org/0000-0001-5487-1117
Tan TaoState Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, China.
Alan TrounsonMonash University, Clayton, Victoria, Australia.
Tushar WarrierEpigenetics and Cell Fates Laboratory, A*STAR Institute of Molecular and Cell Biology, Singapore, Singapore.ORCID http://orcid.org/0000-0003-4839-5067
Elias T ZambidisInstitute for Cell Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Kunming University of Science and Technology · CNAgency for Science, Technology and Research · SGHarvard University · USJohns Hopkins University · USAustralian Regenerative Medicine Institute · AUCalifornia Institute for Regenerative Medicine · USGuangzhou Experimental Station · CNHebrew University of Jerusalem · ILJackson Laboratory · USKyoto University · JPPeking University · CNSalk Institute for Biological Studies · USThe University of Melbourne · AUThe University of Texas Southwestern Medical Center · USWestlake University · CNYale University · US

Funding

Embryonic vascular stem-progenitors for treatment of ischemic retinopathiesR01EY032113 · NEI · JOHNS HOPKINS UNIVERSITY · PI ZAMBIDIS, ELIAS T. · 2021 to 2024
$2.0M
Pluripotent Stem Cell Vascular Therapies for Ischemic RetinopathiesR01EY023962 · NEI · JOHNS HOPKINS UNIVERSITY · PI ZAMBIDIS, ELIAS T. · 2014 to 2018
$1.8M
Functional Vascular Progenitors from Naive Human iPSCR01HD082098 · NICHD · JOHNS HOPKINS UNIVERSITY · PI ZAMBIDIS, ELIAS T. · 2015 to 2019
$1.7M
Origin of HSC from Embryonic Stem CellsK08HL077595 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI ZAMBIDIS, ELIAS T. · 2004 to 2008
$666k
NEI NIH HHS R01 EY023962NEI NIH HHS R01 EY032113NHLBI NIH HHS K08 HL077595NICHD NIH HHS R01 HD082098
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ChimeraEmbryo, MammalianAnimalsHaplorhiniHumans

Identifiers

PMID35879609
PMCPMC9780756
OpenAlexW4287510371

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.