Evidence map›Paper›PMID 35879547›Full record

ArticleNature chemical biology2022

Na

Neil White, Harini Sadeeshkumar, Anna Sun, Narasimhan Sudarsan, Ronald R Breaker

Open access · hybridAbstract read
In one paragraph

Article in Nature chemical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Prokaryotic homeostasis - a solution to thrive and survive.Frontiers in molecular biosciences · 2025
    Review
  9. Review
  10. The current riboswitch landscape inMicrobiology (Reading, England) · 2024
    Review
  11. Article
  12. Article
  13. Gas-sensing riboceptors.RNA biology · 2024
    Article
  14. Riboswitches, from cognition to transformation.Synthetic and systems biotechnology · 2023
    Review
  15. Discovering riboswitches: the past and the future.Trends in biochemical sciences · 2023
    Review
  16. Article
  17. A Riboswitch-Driven Era of New Antibacterials.Antibiotics (Basel, Switzerland) · 2022
    Review
  18. A new class of metal-sensing RNA.Nature chemical biology · 2022
    Article
  19. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Neil White *Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT, USA.ORCID http://orcid.org/0000-0002-4261-9632
Harini Sadeeshkumar *Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT, USA.ORCID http://orcid.org/0000-0001-9976-4040
Anna SunDepartment of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT, USA.ORCID http://orcid.org/0000-0002-4772-4271
Narasimhan SudarsanHoward Hughes Medical Institute, Yale University, New Haven, CT, USA.
Ronald R BreakerDepartment of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT, USA. ronald.breaker@yale.edu.ORCID http://orcid.org/0000-0002-2165-536X
Howard Hughes Medical Institute · USYale University · US

Funding

X-RAY ANALYSIS OF PROTEIN STRUCTURE AND FUNCTIONP01GM022778 · NIGMS · YALE UNIVERSITY · PI BREAKER, RONALD R · 1985 to 2019
$26.1M
Exploiting Riboswitch Sensors to Reveal Antibiotics Uptake and Retention in Gram Negative BacteriaR01AI136794 · NIAID · YALE UNIVERSITY · PI BREAKER, RONALD R, KAZMIERCZAK, BARBARA I · 2018 to 2022
$5.6M
Discovery and Characterization of New RiboswitchesR01GM136969 · NIGMS · YALE UNIVERSITY · PI STROBEL, SCOTT A · 2020 to 2023
$1.6M
Howard Hughes Medical InstituteNIAID NIH HHS R01 AI136794NIGMS NIH HHS P01 GM022778NIGMS NIH HHS R01 GM136969
6 · The paper itself

Abstract

Organisms presumably have mechanisms to monitor and physiologically adapt to changes in cellular Na

Indexed as

Physiological PhenomenaRiboswitchBacteriaGene Expression Regulation, BacterialIonsNucleic Acid ConformationRNA, BacterialSodiumIonsRiboswitchRNA, BacterialSodium

Identifiers

PMID35879547
PMCPMC9337991
OpenAlexW4287509975

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.