Evidence map›Paper›PMID 35879451›Full record

ArticleNature immunology2022

The function of Wtap in N

Taku Ito-Kureha, Cristina Leoni, Kayla Borland, Giulia Cantini, Marian Bataclan, Rebecca N Metzger, Gregor Ammann, Anne B Krug, Annalisa Marsico, Stefanie Kaiser and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 91 citations in OpenAlex.

  1. Trial
  2. Article
  3. WTAP-Mediated mAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  4. Article
  5. Review
  6. WTAP mediated mScience China. Life sciences · 2026
    Article
  7. Regulation of mCell biology and toxicology · 2026
    Review
  8. Lipid metabolism in homeostasis and disease.Signal transduction and targeted therapy · 2026
    Review
  9. mFrontiers in immunology · 2026
    Review
  10. Review
  11. Review
  12. WTAP-mediated mScience China. Life sciences · 2025
    Article
  13. Review
  14. mCancer cell international · 2025
    Article
  15. Article
  16. Article
  17. WTAP/YTHDF1-mediated mJournal of advanced research · 2025
    Article
  18. Regulation and application of mScience China. Life sciences · 2025
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 3 countries.

Taku Ito-KurehaInstitute for Immunology, Biomedical Center, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried, Germany.ORCID 0000-0002-6239-9227
Cristina LeoniInstitute for Research in Biomedicine, Università della Svizzera Italiana, Bellinzona, Switzerland.
Kayla BorlandDepartment of Chemistry, Ludwig-Maximilians-Universität in Munich, Munich, Germany.
Giulia CantiniResearch Unit Molecular Immune Regulation, Helmholtz Zentrum München, Munich, Germany.
Marian BataclanInstitute for Research in Biomedicine, Università della Svizzera Italiana, Bellinzona, Switzerland.
Rebecca N MetzgerInstitute for Immunology, Biomedical Center, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried, Germany.
Gregor AmmannDepartment of Chemistry, Ludwig-Maximilians-Universität in Munich, Munich, Germany.ORCID 0000-0003-2135-058X
Anne B KrugInstitute for Immunology, Biomedical Center, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried, Germany.ORCID 0000-0002-9556-7207
Annalisa MarsicoInstitute for Computational Biology, Helmholtz Zentrum München, Neuherberg, Germany.
Stefanie KaiserDepartment of Chemistry, Ludwig-Maximilians-Universität in Munich, Munich, Germany.
Stefan CanzarGene Center, Ludwig-Maximilians-Universität in Munich, Munich, Germany.ORCID 0000-0003-4719-8010
Stefan FeskeDepartment of Pathology, New York University School of Medicine, New York, NY, USA.
Silvia MonticelliInstitute for Research in Biomedicine, Università della Svizzera Italiana, Bellinzona, Switzerland.ORCID 0000-0002-5909-8802
Julian KönigInstitute of Molecular Biology, Mainz, Germany.ORCID 0000-0002-9398-5421
Vigo HeissmeyerInstitute for Immunology, Biomedical Center, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Planegg-Martinsried, Germany. vigo.heissmeyer@med.uni-muenchen.de.ORCID 0000-0002-2263-8545
Ludwig-Maximilians-Universität München · DEHelmholtz Zentrum München · DEUniversità della Svizzera italiana · CHGoethe University Frankfurt · DEInstitute of Molecular Biology · DENew York University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

T cell antigen-receptor (TCR) signaling controls the development, activation and survival of T cells by involving several layers and numerous mechanisms of gene regulation. N

Indexed as

Cell Cycle ProteinsMethyltransferasesAdenosineAnimalsMethylationMiceRNA, MessengerRNA Splicing FactorsSignal TransductionAdenosineCell Cycle ProteinsMethyltransferasesN(6)-ribosyladenineRNA, MessengerRNA Splicing Factors

Identifiers

PMID35879451
OpenAlexW4287510049

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.