Evidence map›Paper›PMID 35879380›Full record

ArticleScientific reports2022

Analysis of family stigma and socioeconomic factors impact among caregivers of patients with early- and late-onset Alzheimer's disease and frontotemporal dementia.

Lina Velilla, Natalia Acosta-Baena, Isabel Allen, Francisco Lopera, Joel Kramer

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Lina VelillaNeuroscience Group of Antioquia, Medical School Antioquia University, Calle 62 N 52-59, 050010, Medellín, Antioquia, Colombia. lina.velilla@gbhi.org.
Natalia Acosta-BaenaNeuroscience Group of Antioquia, Medical School Antioquia University, Calle 62 N 52-59, 050010, Medellín, Antioquia, Colombia.
Isabel AllenDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA.
Francisco Lopera *Neuroscience Group of Antioquia, Medical School Antioquia University, Calle 62 N 52-59, 050010, Medellín, Antioquia, Colombia.
Joel Kramer *Global Brain Health Institute, Memory and Aging Center University of California San Francisco, 1651 4th St Suite 212, San Francisco, CA, 94143, USA.
Universidad de Antioquia · COGlobal Brain Health Institute · USUniversity of California, San Francisco · US

Funding

Alzheimer's Association GBHI ALZ UK-19-585211
6 · The paper itself

Abstract

To the best of our knowledge, there are no research studies about socioeconomic factors, family stigma, and their psychological impact on early-onset dementia caregivers. We assessed the impact of family stigma and socioeconomic factors on psychological outcomes, quality of life (QoL), and caregiver burden among 150 caregivers of patients with early-onset Alzheimer's disease due to E280A mutation in presenilin 1 (EOAD), frontotemporal dementia (FTD), and late-onset Alzheimer's disease (LOAD). Caregivers of patients with EOAD presented a higher frequency of socioeconomic risk factors. Caregivers of FTD presented higher levels of family stigma and a higher prevalence of negative outcomes. We found family stigma to be a more suitable predictor of all outcomes. After adjusting for the type of dementia, dementia stage and behavioral changes, and caregiver age and education, family stigma was the most important factor associated with a higher risk of caregiver burden and a reduction in QoL in terms of energy fatigue and emotional wellbeing among early-onset dementia caregivers.

Indexed as

Alzheimer DiseaseFrontotemporal DementiaCaregiversHumansLate Onset DisordersQuality of LifeSocioeconomic Factors

Identifiers

PMID35879380
PMCPMC9314345
OpenAlexW4287377719

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.