Evidence map›Paper›PMID 35879109›Full record

ArticleUltrasonography (Seoul, Korea)2022

Brain contrast-enhanced ultrasonography and elastography in infants.

Misun Hwang, Zeng Zhang, Joseph Katz, Colbey Freeman, Todd Kilbaugh

Open access · diamondAbstract read
In one paragraph

Article in Ultrasonography (Seoul, Korea), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Misun HwangDepartment of Radiology, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Zeng ZhangDepartment of Mechanical Engineering, Johns Hopkins University, Baltimore, MD, USA.
Joseph KatzDepartment of Mechanical Engineering, Johns Hopkins University, Baltimore, MD, USA.
Colbey FreemanDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Todd KilbaughDepartment of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Children's Hospital of Philadelphia · USJohns Hopkins University · USUniversity of Pennsylvania · US

Funding

Novel Ultrasound Indices of Intracranial Pressure and Brain Ischemia in Neonatal HydrocephalusR01NS119473 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI Misun Hwang · 2020 to 2026
$4.0M
NINDS NIH HHS R01 NS119473
6 · The paper itself

Abstract

Advanced ultrasound techniques, including brain contrast-enhanced ultrasonography and elastography, are increasingly being explored to better understand infant brain health. While conventional brain ultrasonography provides a convenient, noninvasive means of assessing major intracranial pathologies, its value in revealing functional and physiologic insights into the brain lags behind advanced imaging techniques such as magnetic resonance imaging. In this regard, contrast-enhanced ultrasonography provides highly precise functional information on macrovascular and microvascular perfusion, while brain elastography offers information on brain stiffness that may be associated with relevant physiological factors of diagnostic, therapeutic, and/or prognostic utility. This review details the technical background, current understanding and utility, and future directions of these two emerging advanced ultrasound techniques for neonatal brain applications.

Indexed as

BrainContrast-enhanced ultrasoundElastographyInfants

Identifiers

PMID35879109
PMCPMC9532200
OpenAlexW4220955463

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.