Evidence map›Paper›PMID 35878784›Full record

ArticleAnnals of epidemiology2022

An algorithm to predict data completeness in oncology electronic medical records for comparative effectiveness research.

David Merola, Sebastian Schneeweiss, Deborah Schrag, Joyce Lii, Kueiyu Joshua Lin

Abstract read
In one paragraph

Article in Annals of epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

David MerolaDivision of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA. Electronic address: davemerola@gmail.com.
Sebastian SchneeweissDivision of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA.
Deborah SchragDepartment of Medicine, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical School, New York, NY.
Joyce LiiDepartment of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA.
Kueiyu Joshua LinDivision of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Improving comparative effectiveness research through electronic health records continuity cohortsR01LM012594 · NLM · BRIGHAM AND WOMEN'S HOSPITAL · PI LIN, JOSHUA K · 2017 to 2020
$1.5M
NCI NIH HHS P30 CA008748NLM NIH HHS R01 LM012594
6 · The paper itself

Abstract

introductionElectronic health record (EHR) discontinuity (missing out-of-network encounters) can lead to information bias. We sought to construct an algorithm that identifies high EHR-continuity among oncology patients.

methodsUsing a linked Medicare-EHR database and regression, we sought to 1) measure how often Medicare claims for outpatient encounters were substantiated by visits recorded in the EHR, and 2) predict continuity ratio, defined as the yearly proportion of outpatient encounters reported to Medicare that were captured by EHR data. The prediction model...s performance was evaluated with the coefficient of determination and Spearman...s correlation. We quantified variable misclassification by decile of continuity ratio using standardized difference and sensitivity.

resultsA total of 79,678 subjects met all eligibility criteria. Predicted and observed continuity was highly correlated (σ

conclusionIn the oncology population, restricting EHR-based study cohorts to subjects with high continuity may reduce misclassification without greatly impacting representativeness. Further work is needed to elucidate the best manner of implementing continuity prediction rules in cohort studies.

Indexed as

Electronic Health RecordsNeoplasmsAgedAlgorithmsComparative Effectiveness ResearchHumansMedical OncologyMedicareUnited StatesComparative effectiveness researchContinuityElectronic medical recordsInformation bias

Identifiers

PMID35878784
PMCPMC9741728

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.