Evidence map›Paper›PMID 35878275›Full record

ArticleToxics2022

Transcriptomic Evidence That Switching from Tobacco to Electronic Cigarettes Does Not Reverse Damage to the Respiratory Epithelium.

Giovanna L Pozuelos, Meenakshi Kagda, Matine A Rubin, Maciej L Goniewicz, Thomas Girke, Prue Talbot

Open access · goldAbstract read
In one paragraph

Article in Toxics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. The Toxicological Effects of e-Cigarette Use in the Upper Airway: A Scoping Review.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2024
    Article
  5. Does vaping increase the likelihood of SARS-CoV-2 infection? Paradoxically yes and no.American journal of physiology. Lung cellular and molecular physiology · 2024
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Giovanna L PozuelosDepartment of Molecular, Cell and Systems Biology, University of California, Riverside, CA 92521, USA.
Meenakshi KagdaDepartment of Molecular, Cell and Systems Biology, University of California, Riverside, CA 92521, USA.ORCID 0000-0003-0545-0185
Matine A RubinDepartment of Molecular, Cell and Systems Biology, University of California, Riverside, CA 92521, USA.
Maciej L GoniewiczDepartment of Health Behavior, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.ORCID 0000-0001-6748-3068
Thomas GirkeInstitute for Integrative Genome Biology, University of California, Riverside, CA 92521, USA.ORCID 0000-0003-0710-3777
Prue TalbotDepartment of Molecular, Cell and Systems Biology, University of California, Riverside, CA 92521, USA.ORCID 0000-0001-8833-0845
University of California, Riverside · USRoswell Park Comprehensive Cancer Center · US

Funding

Systems BiologyU19AG023122 · NIA · TRANSLATIONAL GENOMICS RESEARCH INST · PI NICHOLAS Joseph SCHORK · 2004 to 2026
$102.6M
Metals in Electronic Cigarette Aerosol R01DA036493 · NIDA · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI TALBOT, PRUDENCE · 2014 to 2018
$3.6M
NIA NIH HHS U19 AG023122NIDA NIH HHS R01 DA036493NIH HHS R01DA03649
6 · The paper itself

Abstract

The health benefits of switching from tobacco to electronic cigarettes (ECs) are neither confirmed nor well characterized. To address this problem, we used RNA-seq analysis to compare the nasal epithelium transcriptome from the following groups (

Indexed as

cigarette smokeciliogenesiselectronic cigarettesimmune responseoxidative stresssquamous metaplasiatranscriptomic analysis

Identifiers

PMID35878275
PMCPMC9321508
OpenAlexW4283817118

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.