Evidence map›Paper›PMID 35878210›Full record

ArticleToxins2022

Altered RNome expression in Murine Gastrocnemius Muscle following Exposure to Jararhagin, a Metalloproteinase from

Andrezza Nascimento, Bianca Cestari Zychar, Rodrigo Pessôa, Alberto José da Silva Duarte, Patricia Bianca Clissa, Sabri Saeed Sanabani

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Andrezza NascimentoPost-Graduation Program in Translational Medicine, Department of Medicine, Federal University of São Paulo, São Paulo 04021-001, Brazil.
Bianca Cestari ZycharLaboratory of Pathophysiology, Butantan Institute, São Paulo 05503-900, Brazil.ORCID 0000-0002-7125-5380
Rodrigo PessôaPost-Graduation Program in Translational Medicine, Department of Medicine, Federal University of São Paulo, São Paulo 04021-001, Brazil.
Alberto José da Silva DuarteLaboratory of Dermatology and Immunodeficiency, Department of Dermatology LIM 56, Faculty of Medicine, University of São Paulo, São Paulo 05403-000, Brazil.
Patricia Bianca ClissaLaboratory of Immunopathology, Butantan Institute, São Paulo 05503-900, Brazil.
Sabri Saeed SanabaniLaboratory of Dermatology and Immunodeficiency, Department of Dermatology LIM 56, Faculty of Medicine, University of São Paulo, São Paulo 05403-000, Brazil.ORCID 0000-0002-8876-8262
Instituto Butantan · BRUniversidade de São Paulo · BRUniversidade Federal de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Small RNAs (sRNAs) and microRNAs (miRNAs) are small endogenous noncoding single-stranded RNAs that regulate gene expression in eukaryotes. Experiments in mice and humans have revealed that a typical small RNA can affect the expression of a wide range of genes, implying that small RNAs function as global regulators. Here, we used small RNA deep sequencing to investigate how jararhagin, a metalloproteinase toxin produced from the venom of

Indexed as

BothropsCrotalid VenomsMicroRNAsAnimalsBothrops jararaca VenomHumansMetalloendopeptidasesMetalloproteasesMiceMuscle, SkeletalBothrops jararaca VenomCrotalid VenomsMetalloendopeptidasesMetalloproteasesMicroRNAsjararhaginsmall RNAsvenom

Identifiers

PMID35878210
PMCPMC9321239
OpenAlexW4285011030

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.