ReviewToxins2022
Novel Anatomical Proposal for Botulinum Neurotoxin Injection Targeting Lateral Canthal Rhytids.
Review in Toxins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Trial
- Article
- A dual track predictive model for assessing crow's feet aging across different clinical severity grades.Scientific reports · 2026Article
- Layer-Specific Architecture and Nerve Innervation of the Popliteus Muscle: Neuroanatomical Basis for Precision-Guided Interventions for the Knee Joint.Diagnostics (Basel, Switzerland) · 2026Article
- Full-face aesthetic treatment with onabotulinumtoxin A: Results from a retrospective real world analysis.JPRAS open · 2026Article
- Textbook-Ultrasound-Cadaver: A Three-Step Learning Method in Facial Botulinum Toxin Type A Injection.Aesthetic plastic surgery · 2026Article
- Anatomy-Based Filler Injection: Treatment Techniques for Supraorbital Hollowness and Charming Roll.Life (Basel, Switzerland) · 2025Review
- Botulinum toxin treatment for hemifacial spasm: harmonising neurological and aesthetic outcomes.Journal of neural transmission (Vienna, Austria : 1996) · 2025Review
- Synergistic facial rejuvenation with PDO threads and Botulinum Toxin A for aging skin.Case reports in plastic surgery & hand surgery · 2025Article
- Topographic Analysis of the Periorbital Region Including Orbicularis Oculi Muscle Based on Ultrasonography Interpretation.Journal of cosmetic dermatology · 2025Article
- Anatomical perspectives of brow-lifting using threads: Clinical cases with techniques.Journal of cosmetic dermatology · 2024Article
- Extraction and injection of botulinum toxin with less wastage.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024Article
- Sonographic observation of the paradoxical masseteric bulging and clinical implication of functional compartment.Anatomy & cell biology · 2024Article
- Review
- Botulinum neurotoxin injection for treating plunged nose and post-rhinoplasty: anatomical perspectives of depressor septi nasi, nasalis, leveator labii superioris alaeque nasi muscle.Anatomy & cell biology · 2023Review
- Novel anatomical guidelines for botulinum neurotoxin injection in the mentalis muscle: a review.Anatomy & cell biology · 2023Review
- Intramuscular neural distribution of the teres minor muscle using Sihler's stain: application to botulinum neurotoxin injection.Anatomy & cell biology · 2023Article
- Guidance in botulinum neurotoxin injection for lower extremity spasticity: Sihler's staining technique.Surgical and radiologic anatomy : SRA · 2023Review
- Novel anatomical proposal for botulinum neurotoxin injection targeting depressor anguli oris for treating drooping mouth corner.Anatomy & cell biology · 2023Review
- Width of the orbicularis oculi fibers extending to the upper lip with the lateral and inferior lengths of the orbicularis oculi at the lateral canthus level: application to botulinum neurotoxin type A injection for crow's feet.Surgical and radiologic anatomy : SRA · 2023Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Botulinum neurotoxin injections near the lateral canthal rhytids are commonly used in cosmetic settings; however, there is a lack of thorough anatomical knowledge, and an effective way to treat them with accumulating knowledge is needed. The anatomical characteristics concerning the injection of botulinum neurotoxin into the orbicularis oculi muscle were evaluated in this review. Current knowledge on the identification of botulinum neurotoxin injection points from recent anatomical research was assessed. The lateral canthal lines are involved with the orbicularis oculi muscle and nearby anatomical structures, and the injection points can be more precisely defined. The best possible injection sites were provided, and the injection procedure was described. This review proposes evidence for injection sites associated with the surface anatomy of the orbicularis oculi muscles to enhance the effectiveness of easing lateral canthal rhytids.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.