Evidence map›Paper›PMID 35878149›Full record

ArticleTropical medicine and infectious disease2022

Determinants of Patients' Adherence to Malaria Treatment in the Democratic Republic of the Congo.

Nsengi Y Ntamabyaliro, Christian Burri, Yves N Lula, Didier B Nzolo, Aline B Engo, Mireille A Ngale, Hippolyte N Situakibanza, Eric S Mukomena, Gauthier K Mesia, Samuel M Mampunza and 1 more

Abstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Community health workers in clinical research at the example of a phase IIIb/ IV antimalarial drug trial conducted in five African countries.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2023
    Trial
  2. Challenges in Malaria Diagnosis and Treatment in Kinshasa Province, Democratic Republic of the Congo.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nsengi Y NtamabyaliroUnité de Pharmacologie Clinique, Faculté de Médecine, Université de Kinshasa, Kinshasa P.O. Box 834, Democratic Republic of the Congo.ORCID 0000-0003-2929-9301
Christian BurriSwiss Tropical and Public Health Institute, Kreuzstrasse 2, 4123 Allschwil, Switzerland.ORCID 0000-0001-5418-1984
Yves N LulaUnité de Pharmacologie Clinique, Faculté de Médecine, Université de Kinshasa, Kinshasa P.O. Box 834, Democratic Republic of the Congo.
Didier B NzoloUnité de Pharmacologie Clinique, Faculté de Médecine, Université de Kinshasa, Kinshasa P.O. Box 834, Democratic Republic of the Congo.ORCID 0000-0002-1297-9581
Aline B EngoUnité de Pharmacologie Clinique, Faculté de Médecine, Université de Kinshasa, Kinshasa P.O. Box 834, Democratic Republic of the Congo.
Mireille A NgaleUnité de Pharmacologie Clinique, Faculté de Médecine, Université de Kinshasa, Kinshasa P.O. Box 834, Democratic Republic of the Congo.
Hippolyte N SituakibanzaDépartement de Médecine Tropicale, Faculté de Médecine, Université de Kinshasa, Kinshasa P.O. Box 834, Democratic Republic of the Congo.
Eric S MukomenaProgramme National de Lutte Contre le Paludisme, Ministère de la Santé, Av. Du Tourisme Commune de Ngaliema, Kinshasa P.O. Box 3088, Democratic Republic of the Congo.
Gauthier K MesiaUnité de Pharmacologie Clinique, Faculté de Médecine, Université de Kinshasa, Kinshasa P.O. Box 834, Democratic Republic of the Congo.ORCID 0000-0002-2406-2631
Samuel M MampunzaUnité de Pharmacologie Clinique, Faculté de Médecine, Université de Kinshasa, Kinshasa P.O. Box 834, Democratic Republic of the Congo.
Gaston L TonaUnité de Pharmacologie Clinique, Faculté de Médecine, Université de Kinshasa, Kinshasa P.O. Box 834, Democratic Republic of the Congo.

Funding

Global Fund to Fight AIDS, Tuberculosis and Malaria NMF1
6 · The paper itself

Abstract

(1) Background: Malaria heavily affects the Democratic Republic of the Congo (DRC) despite the use of effective drugs. Poor adherence to malaria treatment may contribute to this problem. (2) Methods: In one rural and one urban health area in each of the 11 former provinces of the DRC, all households with a case of malaria in the 15 days preceding the survey were selected and the patients or caregivers were interviewed. Adherence to malaria treatment was assessed by self-declaration about its completion. Logistic regression was used to assess predictors. (3) Results: 1732 households participated. Quinine was the most used drug; adherence to artesunate-amodiaquine was the lowest and the main reason for treatment discontinuation was adverse reactions. Predictors of adherence were residence in an urban area, university education, catholic religion, and adoption of recommended behaviour towards a malaria case. Adherence was significantly lower for responders who obtained information on antimalarials from Community Health Workers (CHW). (4) Conclusions: Usage of recommended drugs and adherence to malaria treatment need to be promoted, especially in rural areas, and CHW involvement needs to be improved. Awareness messages need to be made accessible and comprehensible to poorly educated populations and churches need to be involved.

Indexed as

adherencemalariatreatment

Identifiers

PMID35878149
PMCPMC9318296

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.