ArticleTropical medicine and infectious disease2022
Post-Mortem Diagnosis of Pediatric Dengue Using Minimally Invasive Autopsy during the COVID-19 Pandemic in Brazil.
Article in Tropical medicine and infectious disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 5 citations in OpenAlex.
- Knowledge, acceptability, and attitudes regarding minimally invasive tissue sampling (MITS) techniques in Brazil.PLOS global public health · 2026Article
- Emerging Diseases/Viruses Prevention, Control, Surveillance, and One Health.Tropical medicine and infectious disease · 2023Article
- Special Issue "Emerging Diseases/Viruses: Prevention, Control, Surveillance, and One Health".Tropical medicine and infectious disease · 2022Article
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14 authors at 5 institutions in 2 countries.
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Abstract
We report the first pediatric disease in which the use of minimally invasive autopsy (MIA) confirmed severe dengue as the cause of death. During the COVID-19 pandemic, a previously healthy 10-year-old girl living in north-eastern Brazil presented fever, headache, diffuse abdominal pain, diarrhoea, and vomiting. On the fourth day, the clinical symptoms worsened and the patient died. An MIA was performed, and cores of brain, lungs, heart, liver, kidneys, and spleen were collected with 14G biopsy needles. Microscopic examination showed diffuse oedema and congestion, pulmonary intra-alveolar haemorrhage, small foci of midzonal necrosis in the liver, and tubular cell necrosis in the kidneys. Dengue virus RNA and NS1 antigen were detected in blood and cerebrospinal fluid samples. Clinical, pathological, and laboratory findings, in combination with the absence of other lesions and microorganisms, allowed concluding that the patient had died from complications of severe dengue.
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