Evidence map›Paper›PMID 35877723›Full record

ReviewMarine drugs2022

An Update of Lectins from Marine Organisms: Characterization, Extraction Methodology, and Potential Biofunctional Applications.

Mirja Kaizer Ahmmed, Shuva Bhowmik, Stephen G Giteru, Md Nazmul Hasan Zilani, Parise Adadi, Shikder Saiful Islam, Osman N Kanwugu, Monjurul Haq, Fatema Ahmmed, Charlene Cheuk Wing Ng and 7 more

Open access · goldAbstract readReview
In one paragraph

Review in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Afil, a Lectin fromMicroorganisms · 2025
    Article
  6. Review
  7. Article
  8. Review
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  10. Article
  11. Article
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 11 institutions in 7 countries.

Mirja Kaizer AhmmedDepartment of Food Sciences, University of Otago, P.O. Box 56, Dunedin 9054, New Zealand.ORCID 0000-0003-4467-0615
Shuva BhowmikCentre for Bioengineering and Nanomedicine, Faculty of Dentistry, Division of Health Sciences, University of Otago, P.O. Box 56, Dunedin 9054, New Zealand.ORCID 0000-0002-3858-7359
Stephen G GiteruDepartment of Food Sciences, University of Otago, P.O. Box 56, Dunedin 9054, New Zealand.ORCID 0000-0001-5278-8424
Md Nazmul Hasan ZilaniDepartment of Pharmacy, Jashore University of Science and Technology, Jashore 7408, Bangladesh.ORCID 0000-0002-5339-6665
Parise AdadiDepartment of Food Sciences, University of Otago, P.O. Box 56, Dunedin 9054, New Zealand.ORCID 0000-0003-4724-9463
Shikder Saiful IslamInstitute for Marine and Antarctic Studies, University of Tasmania, Launceston 7250, Australia.ORCID 0000-0001-7134-6736
Osman N KanwuguInstitute of Chemical Engineering, Ural Federal University, Mira Street 28, 620002 Yekaterinburg, Russia.ORCID 0000-0003-3887-1058
Monjurul HaqDepartment of Fisheries and Marine Bioscience, Jashore University of Science and Technology, Jashore 7408, Bangladesh.ORCID 0000-0001-8498-2619
Fatema AhmmedDepartment of Chemistry, University of Otago, P.O. Box 56, Dunedin 9054, New Zealand.
Charlene Cheuk Wing NgMedway Maritime Hospital, Medway NHS Foundation Trust, Kent ME7 5NY, UK.
Yau Sang ChanDepartment of Obstetrics & Gynaecology, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.ORCID 0000-0003-4000-9037
Md AsadujjamanDepartment of Aquaculture, Faculty of Fisheries and Ocean Sciences, Khulna Agricultural University, Khulna 9100, Bangladesh.
Gabriel Hoi Huen ChanDivision of Science, Engineering and Health Studies, College of Professional and Continuing Education, The Hong Kong Polytechnic University, Hong Kong, China.
Ryno NaudeDepartment of Biochemistry and Microbiology, Nelson Mandela University, Port Elizabeth 6031, South Africa.
Alaa El-Din Ahmed BekhitDepartment of Food Sciences, University of Otago, P.O. Box 56, Dunedin 9054, New Zealand.ORCID 0000-0003-2569-8620
Tzi Bun NgSchool of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Jack Ho WongSchool of Health Sciences, Caritas Institute of Higher Education, Hong Kong, China.
University of Otago · NZKhulna University · BDChattogram Veterinary and Animal Sciences University · BDChinese University of Hong Kong · HKHong Kong Polytechnic University · HKMedway NHS Foundation Trust · GBNelson Mandela University · ZANoakhali Science and Technology University · BDSaint Francis University · HKUniversity of Hong Kong · HKUral Federal University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lectins are a unique group of nonimmune carbohydrate-binding proteins or glycoproteins that exhibit specific and reversible carbohydrate-binding activity in a non-catalytic manner. Lectins have diverse sources and are classified according to their origins, such as plant lectins, animal lectins, and fish lectins. Marine organisms including fish, crustaceans, and mollusks produce a myriad of lectins, including rhamnose binding lectins (RBL), fucose-binding lectins (FTL), mannose-binding lectin, galectins, galactose binding lectins, and C-type lectins. The widely used method of extracting lectins from marine samples is a simple two-step process employing a polar salt solution and purification by column chromatography. Lectins exert several immunomodulatory functions, including pathogen recognition, inflammatory reactions, participating in various hemocyte functions (e.g., agglutination), phagocytic reactions, among others. Lectins can also control cell proliferation, protein folding, RNA splicing, and trafficking of molecules. Due to their reported biological and pharmaceutical activities, lectins have attracted the attention of scientists and industries (i.e., food, biomedical, and pharmaceutical industries). Therefore, this review aims to update current information on lectins from marine organisms, their characterization, extraction, and biofunctionalities.

Indexed as

Aquatic OrganismsPlant LectinsAnimalsFishesGalectinsGlycoproteinsLectins, C-TypeGalectinsGlycoproteinsLectins, C-TypePlant Lectinsadhesinsbio-functional rolescharacterizationextraction and purificationhemagglutininsimmunomodulationmarine lectins

Identifiers

PMID35877723
PMCPMC9316650
OpenAlexW4283717647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.