Evidence map›Paper›PMID 35877482›Full record

ArticleGels (Basel, Switzerland)2022

Gelatinase Responsive Nanogel for Antibacterial Phototherapy and Wound Healing.

Qianqian Han, Xuan Wang, Lin Qiu, Xinpei Zhou, Zexuan Hui, Xinye Ni, Yang Xuan, Xiaoling Lei, Jianhao Wang

Open access · goldAbstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Qianqian HanSchool of Pharmacy, Changzhou University, Changzhou 213164, China.
Xuan WangSchool of Pharmacy, Changzhou University, Changzhou 213164, China.
Lin QiuSchool of Pharmacy, Changzhou University, Changzhou 213164, China.ORCID 0000-0002-6514-6006
Xinpei ZhouSchool of Pharmacy, Changzhou University, Changzhou 213164, China.
Zexuan HuiSchool of Pharmacy, Changzhou University, Changzhou 213164, China.
Xinye NiThe Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou 213003, China.
Yang XuanKey Lab of Biotechnology and Bioresources Utilization of Ministry of Education, College of Life Science, Dalian Minzu University, Dalian 116600, China.
Xiaoling LeiCollege of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.
Jianhao WangSchool of Pharmacy, Changzhou University, Changzhou 213164, China.
Changzhou University · CNChangzhou No.2 People's Hospital · CNHuazhong University of Science and Technology · CNMinzu University of China · CN

Funding

Joint Research Fund Liaoning-Shenyang National Laboratory for Materials Science 2019JH3/30100011National Natural Science Foundation of China 82001894Open Fund of Key Laboratory of Biotechnology and Bioresources Utilization (Dalian Minzu University), Ministry of Education KF2022001QingLan Project of Jiangsu Province none
6 · The paper itself

Abstract

The unique bactericidal mechanism of metal nanoparticles (MNPs) is considered to be an effective strategy to deal with antibiotic resistance, but the oxidative stress damage caused by excessive accumulation of MNPs to normal cells cannot be ignored. Achieving on-demand release of nano-drugs in specific infection environments is highly attractive. Herein, we constructed a "core-shell" nanogel (G@CuS) based on a copper sulfide (CuS) antimicrobial agent and gelatin for targeted drug release and bacterial clearance in a gelatinase infected microenvironment. G@CuS produced heat and reactive oxygen species (ROS) under the irradiation of a laser, which together with the released Cu

Indexed as

antibacterial activityCuS NDsgelatin nanogeltargeted drug releasewound healing

Identifiers

PMID35877482
PMCPMC9320007
OpenAlexW4283393763

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.