Evidence map›Paper›PMID 35877424›Full record

ArticleCurrent issues in molecular biology2022

Patients with Infections of The Central Nervous System Have Lowered Gut Microbiota Alpha Diversity.

Marta Grochowska, Tomasz Laskus, Marcin Paciorek, Agnieszka Pollak, Urszula Lechowicz, Michał Makowiecki, Andrzej Horban, Marek Radkowski, Karol Perlejewski

Open access · goldAbstract read
In one paragraph

Article in Current issues in molecular biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
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  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Marta GrochowskaDepartment of Immunopathology of Infectious and Parasitic Diseases, Medical University of Warsaw, 02-106 Warsaw, Poland.
Tomasz LaskusDepartment of Adult Infectious Diseases, Medical University of Warsaw, 01-201 Warsaw, Poland.
Marcin PaciorekDepartment of Adult Infectious Diseases, Medical University of Warsaw, 01-201 Warsaw, Poland.
Agnieszka PollakDepartment of the Medical Genetics, Medical University of Warsaw, 02-106 Warsaw, Poland.
Urszula LechowiczDepartment of Genetics and Clinical Immunology, National Institute of Tuberculosis and Lung Diseases, 01-138 Warsaw, Poland.ORCID 0000-0002-2645-8779
Michał MakowieckiDepartment of Adult Infectious Diseases, Medical University of Warsaw, 01-201 Warsaw, Poland.
Andrzej HorbanDepartment of Adult Infectious Diseases, Medical University of Warsaw, 01-201 Warsaw, Poland.
Marek RadkowskiDepartment of Immunopathology of Infectious and Parasitic Diseases, Medical University of Warsaw, 02-106 Warsaw, Poland.
Karol PerlejewskiDepartment of Immunopathology of Infectious and Parasitic Diseases, Medical University of Warsaw, 02-106 Warsaw, Poland.ORCID 0000-0002-3782-6442
Medical University of Warsaw · PL

Funding

National Science Center 2017/25/B/NZ6/01463
6 · The paper itself

Abstract

There are multiple lines of evidence for the existence of communication between the central nervous system (CNS), gut, and intestinal microbiome. Despite extensive analysis conducted on various neurological disorders, the gut microbiome was not yet analyzed in neuroinfections. In the current study, we analyzed the gut microbiome in 47 consecutive patients hospitalized with neuroinfection (26 patients had viral encephalitis/meningitis; 8 patients had bacterial meningitis) and in 20 matched for age and gender health controls. Using the QIIME pipeline, 16S rRNA sequencing and classification into operational taxonomic units (OTUs) were performed on the earliest stool sample available. Bacterial taxa such as

Indexed as

16S rRNA sequencingencephalitisgut microbiomeneuroinfection

Identifiers

PMID35877424
PMCPMC9318043
OpenAlexW4283720722

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.