Evidence map›Paper›PMID 35877010›Full record

ArticleArchives of microbiology2022

Antibacterial effect of the combination of terpenoids.

Takayoshi Yamaguchi

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The Antiviral Potential ofMolecules (Basel, Switzerland) · 2024
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
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  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Anti-Evidence-based complementary and alternative medicine : eCAM · 2024
    Article
  17. Nano-Drug Delivery Systems Based on Natural Products.International journal of nanomedicine · 2024
    Review
  18. Pharmacophylogenetic relationships of genusFrontiers in pharmacology · 2024
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Takayoshi YamaguchiDepartment of Food and Nutrition Science, Koran Women's Junior College, 1 Chome-2-1Yokote, Minami-ku, Fukuoka, 811-1311, Japan. yamaguchi@g.koran.ac.jp.ORCID http://orcid.org/0000-0002-7297-2728

Funding

Japan Society for the Promotion of Science KAKENHI JP21K14811
6 · The paper itself

Abstract

Terpenoids are natural compounds originating from five-carbon isoprene units. Over 60,000 terpenoid structures have been identified, and they contribute to the flavor, color, growth, and development of plants. There are several reports on various physiological activities of terpenoids, such as antioxidative and anticancer activities. This study revealed that combinations of terpenoids have activities against a spectrum of bacteria. The combination of carvacrol and thymol has bacteriostatic and bactericidal activities. Four terpenoids (carvacrol, thymol, eugenol, and nootkatone) exhibited bacteriostatic and bactericidal activities when used at low concentrations for 5‒10 min. The most effective bactericidal activity was observed for gram-negative bacteria. A very weak bactericidal activity was observed against Staphylococcus aureus and Enterococcus faecalis. This study revealed the antibacterial potential of different combinations of terpenoids against several bacteria that were tested. Thus, new candidates for the development of antibacterial medicines are reported here for the effective treatment of infectious bacterial diseases.

Indexed as

TerpenesThymolAnti-Bacterial AgentsEugenolMicrobial Sensitivity TestsStaphylococcus aureusAnti-Bacterial AgentsEugenolTerpenesThymolBactericidal actionBacteriostatic activityCombinationTerpenoid

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.