Evidence map›Paper›PMID 35877007›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2022

Shared burden: the association between cancer diagnosis, financial toxicity, and healthcare cost-related coping mechanisms by family members of non-elderly patients in the USA.

Bahaa Kazzi, Fumiko Chino, Brigitte Kazzi, Bhav Jain, Sibo Tian, Joseph A Paguio, J Seth Yao, Vinayak Muralidhar, Brandon A Mahal, Paul L Nguyen and 2 more

Abstract read
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In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
10.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 39 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Review
  6. Integrating Cancer Education Into High School Curricula.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Financial toxicity of hemophilia care in Southeast Asian countries.The Lancet regional health. Southeast Asia · 2025
    Review
  13. Observational
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Understanding the family financial toxicity of cancer through the lens of US patients of South Asian descent.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 1 country.

Bahaa KazziDepartment of Biology, Emory University, Atlanta, GA, USA.
Fumiko ChinoDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 02446, USA.
Brigitte KazziDepartment of Internal Medicine, Johns Hopkins University, Baltimore, MD, USA.
Bhav JainDepartment of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.
Sibo TianDepartment of Radiation Oncology, Emory University School of Medicine, Atlanta, GA, USA.
Joseph A PaguioDepartment of Medicine, Einstein Medical Center, Philadelphia, PA, USA.
J Seth YaoDepartment of Medicine, Einstein Medical Center, Philadelphia, PA, USA.
Vinayak MuralidharDepartment of Radiation Oncology, Kaiser Permanente, Portland, OR, USA.
Brandon A MahalDepartment of Radiation Oncology, University of Miami/Sylvester Comprehensive Cancer Center, Miami, FL, USA.
Paul L NguyenDepartment of Radiation Oncology, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Nina N SanfordDepartment of Radiation Oncology, University of Texas Southwestern, 2280 Inwood Road, Dallas, TX, 75235, USA. nina.sanford@utsouthwestern.edu.
Edward Christopher DeeDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 02446, USA. DeeE1@mskcc.org.ORCID http://orcid.org/0000-0001-6119-0889
Einstein Medical Center Philadelphia · USJohns Hopkins University · USMemorial Sloan Kettering Cancer Center · USBrigham and Women's Hospital · USEmory University · USKaiser Permanente Center for Health Research · USMassachusetts Institute of Technology · USSouthwestern Medical Center · USUniversity of Miami · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NIH/NCI Cancer Center Support R01-CA240582
6 · The paper itself

Abstract

purposeThere has been little research on the healthcare cost-related coping mechanisms of families of patients with cancer. Therefore, we assessed the association between a cancer diagnosis and the healthcare cost-related coping mechanisms of participant family members through their decision to forego or delay seeking medical care, one of the manifestations of financial toxicity.

methodsUsing data from the National Health Interview Survey (NHIS) between 2000 and 2018, sample weight-adjusted prevalence was calculated and multivariable logistic regressions defined adjusted odds ratios (aORs) for participant family members who needed but did not get medical care or who delayed seeking medical care due to cost in the past 12 months, adjusting for relevant sociodemographic covariates, including participant history of cancer (yes vs. no) and participant age (18-45 vs. 46-64 years old). The analysis of family members foregoing or delaying medical care was repeated using a cancer diagnosis * age interaction term.

resultsParticipants with cancer were more likely than those without a history of cancer to report family members delaying (19.63% vs. 16.31%, P < 0.001) or foregoing (14.53% vs. 12.35%, P = 0.001) medical care. Participants with cancer in the 18 to 45 years old age range were more likely to report family members delaying (p

conclusionA cancer diagnosis may be associated with familial healthcare cost-related coping mechanisms, one of the manifestations of financial toxicity. This is seen through delayed/omitted medical care of family members of people with a history of cancer, an association that may be stronger among young adult cancer survivors. These findings underscore the need to further explore how financial toxicity associated with a cancer diagnosis can affect patients' family members and to design interventions to mitigate healthcare cost-related coping mechanisms.

Indexed as

Health ExpendituresNeoplasmsAdaptation, PsychologicalAdolescentAdultFamilyFemaleFinancial StressHealth Care CostsHumansMiddle AgedUnited StatesYoung AdultCancer disparitiesCancer survivorshipFinancial toxicityYoung adult cancer

Identifiers

PMID35877007
OpenAlexW4287147603

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.