Evidence map›Paper›PMID 35876912›Full record

ArticleParasitology research2022

Piroplasmid infection is not associated with clinicopathological and laboratory abnormalities in cats from Midwestern Brazil.

Camila Manoel de Oliveira, Sharon Yang, Matheus Almeida Duarte, Daniela Maciel Figueiredo, Liliane Maria do Rosario Batista, Henry Marr, Concepta Margaret McManus, Marcos Rogério André, Adam Joseph Birkenheuer, Giane Regina Paludo

Open access · greenAbstract read
In one paragraph

Article in Parasitology research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  3. Description ofInternational journal for parasitology. Parasites and wildlife · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Camila Manoel de OliveiraLaboratório de Patologia Clínica Veterinária, Faculdade de Agronomia E Medicina Veterinária (FAV/UnB), Universidade de Brasília, CEP, Campus Universitário Darcy Ribeiro, ICC Centro - Asa Norte, Brasília, Distrito Federal, 70910-900, Brazil.
Sharon YangDepartment of Clinical Sciences, North Carolina State College of Veterinary Medicine, Raleigh, NC, USA.
Matheus Almeida DuarteLaboratório de Patologia Clínica Veterinária, Faculdade de Agronomia E Medicina Veterinária (FAV/UnB), Universidade de Brasília, CEP, Campus Universitário Darcy Ribeiro, ICC Centro - Asa Norte, Brasília, Distrito Federal, 70910-900, Brazil.
Daniela Maciel FigueiredoLaboratório de Patologia Clínica Veterinária, Faculdade de Agronomia E Medicina Veterinária (FAV/UnB), Universidade de Brasília, CEP, Campus Universitário Darcy Ribeiro, ICC Centro - Asa Norte, Brasília, Distrito Federal, 70910-900, Brazil.
Liliane Maria do Rosario BatistaLaboratório de Patologia Clínica Veterinária, Faculdade de Agronomia E Medicina Veterinária (FAV/UnB), Universidade de Brasília, CEP, Campus Universitário Darcy Ribeiro, ICC Centro - Asa Norte, Brasília, Distrito Federal, 70910-900, Brazil.
Henry MarrDepartment of Clinical Sciences, North Carolina State College of Veterinary Medicine, Raleigh, NC, USA.
Concepta Margaret McManusDepartamento de Ciências Fisiológicas, Instituto de Ciências Biológicas, Universidade de Brasília, Brasília, DF, Brazil.
Marcos Rogério AndréLaboratório de Imunoparasitologia, Departamento de Patologia Veterinária, Faculdade de Ciências Agrárias E Veterinárias Júlio de Mesquita Filho (UNESP), Jaboticabal, São Paulo, Brazil.
Adam Joseph BirkenheuerDepartment of Clinical Sciences, North Carolina State College of Veterinary Medicine, Raleigh, NC, USA.
Giane Regina PaludoLaboratório de Patologia Clínica Veterinária, Faculdade de Agronomia E Medicina Veterinária (FAV/UnB), Universidade de Brasília, CEP, Campus Universitário Darcy Ribeiro, ICC Centro - Asa Norte, Brasília, Distrito Federal, 70910-900, Brazil. giane@unb.br.ORCID http://orcid.org/0000-0002-9112-1718
Universidade de Brasília · BRUniversidade Estadual Paulista (Unesp) · BR

Funding

Comparative Medicine and Translational Research Training ProgramT32OD011130 · OD · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Lauren Virginia Schnabel · 2012 to 2026
$7.8M
NIH HHS T32 OD011130
6 · The paper itself

Abstract

Feline piroplasmids include the genera Babesia spp., Cytauxzoon spp., and Theileria spp. In Brazil, there are few reports regarding these hemoprotozoans; however, clinicopathological and molecular data are scarce. This study aimed to characterize the clinical relevance of these parasites through hematological, biochemical, and molecular approaches. For this purpose, 166 cats from Brasilia, Federal District, Midwestern Brazil, were screened using a quantitative polymerase chain reaction (qPCR) for piroplasmids based on the LSU4 mitochondrial gene, which resulted in an overall prevalence of 36/166 (21.7%). Twelve of 166 samples (7.2%) were positive for C. felis, while 19/166 (11.4%) were positive for Babesia vogeli. No samples tested positive for Theileria spp. Babesia vogeli and Cytauxzoon spp. LSU4 sequences showed identities of 97-100% and 99.3%, respectively, to US isolates. The hematological and biochemical findings did not differ significantly between the cats that tested positive and negative for piroplasmids. Although the lack of abnormalities in clinical and laboratory parameters does not eliminate the possibility that these cats were sick and recovered, it may suggest that the Brazilian strain of Cytauxzoon spp. is not as pathogenic as that from the USA, despite the high molecular identity with North American isolates.

Indexed as

BabesiaBabesiosisCat DiseasesFelisPiroplasmidaTheileriaAnimalsBrazilCatsBabesia vogeliBiochemistryCytauxzoon spp.FelineHematologyPiroplasmida

Identifiers

PMID35876912
PMCPMC10680102
OpenAlexW4287147595

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.