ArticleArchives of gynecology and obstetrics2022
Development of a quality of life questionnaire for transgender individuals during hormone therapy (iTransQol).
Article in Archives of gynecology and obstetrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 16 citations in OpenAlex.
- Patient-reported outcomes, provider-reported outcomes, and physiologic parameters after gender-affirming hormone treatment in Canada: a systematic review.Hormones (Athens, Greece) · 2025Pooled it
- Pooled it
- Implementation of Patient-Reported Outcome Measures for Gender-Affirming Care Worldwide: A Systematic Review.JAMA network open · 2023Pooled it
- The Impact of Birth Year on the Coming Out Process for Transgender and Gender Diverse Individuals from Austria.Archives of sexual behavior · 2026Article
- Facial Feminization Surgery and Quality of Life in Transgender Women: Protocol for a Cohort Study.JMIR research protocols · 2025Article
- Provision of gender-affirming care for trans and gender-diverse adults: a systematic review of health and quality of life outcomes, values and preferences, and costs.EClinicalMedicine · 2025Review
- Provision of gender-affirming hormones for trans and gender-diverse adults: a systematic review of health and quality of life outcomes, values and preferences, and costs.EClinicalMedicine · 2025Review
- General and transgender-specific quality of life in trans persons assigned female at birth: validation of the Essen Transgender Quality of Life-Inventory.Sexual medicine · 2025Article
- Development of a fibromyalgia-specific quality of life instrument: the Fibromyalgia Quality of Life Scale (FM-QoLS).Rheumatology international · 2025Article
- Prioritizing Equity: A Call to Implement Freely Available and Accessible Patient-Reported Outcome Measures in Paediatric Gender-Affirming Care.Paediatrics & child health · 2025Article
- The vaginal microbiome of transgender men receiving gender-affirming hormonal therapy in comparison to that of cisgender women.Scientific reports · 2024Article
- Validation of Lower Urinary Tract Symptom Questionnaire in the Transmasculine Population.International urogynecology journal · 2024Observational
- Implementing strategies to improve uptake of patient-reported outcome measures (PROMs) in gender-affirming care: a mixed-methods implementation study.BMJ open quality · 2024Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeQuality of life (QoL) is a complex term, including mental, physical and social health, and everyone's individual environment. While transgender individuals still often report lower QoL than other individuals, they can benefit substantially from gender affirming therapy. The aim of this study was to develop a questionnaire to determine QoL in transgender individuals during gender affirming hormone therapy (GAHT).
methodsA multi-step questionnaire development process was performed. In phase 1, a list of key issues was established by reviewing relevant literature. In phase 2, n = 38 transgender individuals as well as n = 6 practitioners evaluated the questionnaire (iTransQoL) in terms of relevance, meaning, comprehensibility and redundancy. Psychometric testing of the questionnaire was performed in phase 3 with n = 40 transgender individuals. The external validity of the iTransQoL was tested by comparison with three validated health questionnaires.
resultsThe exploratory factor analysis indicated an underlying four-factor solution. Psychometric testing showed acceptable to good overall reliability (α = 0.73-0.83) for the total score and the four subscales as well as good validity indices. Based on the results, a final version of the iTransQoL was established.
conclusionThe iTransQoL is a reliable and valid tool to evaluate QoL of transgender individuals during GAHT.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.