ArticleEuropean journal of nuclear medicine and molecular imaging2022
EARL compliance and imaging optimisation on the Biograph Vision Quadra PET/CT using phantom and clinical data.
Article in European journal of nuclear medicine and molecular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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26 citing papers in PubMed.
- From sensitivity gain to clinical decisions: total-body and long-axial-field-of-view PET/CT for diagnosis and image-based management in oncology and systemic disease.Annals of nuclear medicine · 2026Review
- Coronary artery disease imaging with total-body PET.The British journal of radiology · 2026Review
- Sex- and Age-Related Differences in Physiological [Bioengineering (Basel, Switzerland) · 2026Article
- Parametric analysis of dynamic long axial field-of-viewEJNMMI physics · 2026Article
- Total-body [European journal of nuclear medicine and molecular imaging · 2026Article
- Harmonisation of standard uptake values in long-axial field-of-view PET/CT: an exploratory study.EJNMMI physics · 2026Article
- Impact of the maximum ring difference on image quality and noise characteristics of a total-body PET/CT scanner.Zeitschrift fur medizinische Physik · 2025Article
- Effect of probenecid on the whole-body disposition of 6-bromo-7-[European journal of nuclear medicine and molecular imaging · 2025Article
- SNMMI Procedure Standard/EANM Practice Guideline for Fibroblast Activation Protein (FAP) PET.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025Article
- The significance of PET/CT combined with machine learning models for the classification of lymphoma involvement and metastases in enlarged lymph nodes.Frontiers in oncology · 2025Article
- EARL compliance on the Biograph Vision Quadra PET-CT: phantom study for static and continuous bed motion acquisitions.Frontiers in nuclear medicine · 2025Article
- Long-Axial Field-of-View PET Imaging in Patients with Lymphoma: Challenges and Opportunities.PET clinics · 2024Review
- Clinical Performance Comparison of a Long Versus a Short Axial Field-of-View PET/CT Using EARL-Compliant Reconstructions.Molecular imaging and biology · 2024Article
- Ultra-low foetal radiation exposure inEJNMMI physics · 2024Article
- Mitigating SUV uncertainties using total body PET imaging.European journal of nuclear medicine and molecular imaging · 2024Article
- Optimization of Y-90 Radioembolization Imaging for Post-Treatment Dosimetry on a Long Axial Field-of-View PET/CT Scanner.Diagnostics (Basel, Switzerland) · 2023Article
- Image Quality and Quantitative PET Parameters of Low-Dose [Diagnostics (Basel, Switzerland) · 2023Article
- [Diagnostics (Basel, Switzerland) · 2023Review
- Collection on total-body PET.EJNMMI physics · 2023Article
- AI Transformers for Radiation Dose Reduction in Serial Whole-Body PET Scans.Radiology. Artificial intelligence · 2023Article
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11 authors.
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Abstract
purposeCurrent European Association of Nuclear Medicine (EANM) Research Ltd. (EARL) guidelines for the standardisation of PET imaging developed for conventional systems have not yet been adjusted for long axial field-of-view (LAFOV) systems. In order to use the LAFOV Siemens Biograph Vision Quadra PET/CT (Siemens Healthineers, Knoxville, TN, USA) in multicentre research and harmonised clinical use, compliance to EARL specifications for
methodsEARL compliance phantom measurements were performed using the NEMA image quality phantom both in the centre and at various locations throughout the LAFOV. PET data (maximum ring difference (MRD) = 85) were reconstructed using various reconstruction parameters and reprocessed to obtain images at shorter scan durations. Maximum, mean and peak activity concentration recovery coefficients (RC) were obtained for each sphere and compared to EARL standards specifications. Additionally, PET data (MRD = 85) of 10 oncological patients were acquired and reconstructed using various reconstruction settings and reprocessed from 10 min listmode acquisition into shorter scan durations. Per dataset, SUVs were derived from tumour lesions and healthy tissues. ANOVA repeated measures were performed to explore differences in lesion SUV
resultsPhantom measurements showed EARL compliance for all positions throughout the LAFOV for all scan durations. Regarding patient data, EARL-compliant images showed no clinically meaningful significant differences in lesion SUV
conclusionImages obtained using the Vision Quadra PET/CT comply with EARL specifications. Scan duration and/or activity administration can be reduced up to a factor tenfold without the interference of increased noise.
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