Evidence map›Paper›PMID 35876567›Full record

ArticleApplied and environmental microbiology2022

RasI/R Quorum Sensing System Controls the Virulence of

Jinli Yan, Peng Li, Xiaoqing Wang, Minya Zhu, Hongyu Shi, Guohui Yu, Xuemei Chen, Huishan Wang, Xiaofan Zhou, Lisheng Liao and 1 more

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. The role of MorI/MorR quorum sensing inMicrobiology spectrum · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Proposal to classifyFrontiers in microbiology · 2023
    Article
  16. Frontiers in plant science · 2023
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Jinli Yan *Guangdong Laboratory of Microbial Signals and Disease Control, Integrative Microbiology Research Centre, South China Agricultural Universitygrid.20561.30, Guangzhou, China.
Peng Li *Ministry of Education Key Laboratory for Ecology of Tropical Islands, Key Laboratory of Tropical Animal and Plant Ecology of Hainan Province, College of Life Sciences, Hainan Normal University, Haikou, China.
Xiaoqing WangGuangdong Laboratory of Microbial Signals and Disease Control, Integrative Microbiology Research Centre, South China Agricultural Universitygrid.20561.30, Guangzhou, China.
Minya ZhuGuangdong Laboratory of Microbial Signals and Disease Control, Integrative Microbiology Research Centre, South China Agricultural Universitygrid.20561.30, Guangzhou, China.
Hongyu ShiGuangdong Laboratory of Microbial Signals and Disease Control, Integrative Microbiology Research Centre, South China Agricultural Universitygrid.20561.30, Guangzhou, China.
Guohui YuInstitute of Plant Health, Zhongkai University of Agriculture and Engineeringgrid.449900.0, Guangzhou, China.
Xuemei ChenCollege of Forestry and Landscape Architecture, South China Agricultural Universitygrid.20561.30, Guangzhou, China.
Huishan WangGuangdong Laboratory of Microbial Signals and Disease Control, Integrative Microbiology Research Centre, South China Agricultural Universitygrid.20561.30, Guangzhou, China.
Xiaofan ZhouGuangdong Laboratory of Microbial Signals and Disease Control, Integrative Microbiology Research Centre, South China Agricultural Universitygrid.20561.30, Guangzhou, China.
Lisheng LiaoGuangdong Laboratory of Microbial Signals and Disease Control, Integrative Microbiology Research Centre, South China Agricultural Universitygrid.20561.30, Guangzhou, China.ORCID 0000-0002-6844-4113
Lianhui ZhangGuangdong Laboratory of Microbial Signals and Disease Control, Integrative Microbiology Research Centre, South China Agricultural Universitygrid.20561.30, Guangzhou, China.ORCID 0000-0002-4298-7988
South China Agricultural University · CNHainan Normal University · CNZhongkai University of Agriculture and Engineering · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quorum sensing (QS) is a widely conserved bacterial regulatory mechanism that relies on production and perception of autoinducing chemical signals to coordinate diverse cooperative activities, such as virulence, exoenzyme secretion, and biofilm formation. In Ralstonia solanacearum, a phytopathogen causing severe bacterial wilt diseases in many plant species, previous studies identified the PhcBSR QS system, which plays a key role in regulation of its physiology and virulence. In this study, we found that R. solanacearum strain EP1 contains the genes encoding uncharacterized LuxI/LuxR (LuxI/R) QS homologues (RasI/RasR [designated RasI/R here]). To determine the roles of the RasI/R system in strain EP1, we constructed a specific reporter for the signals catalyzed by RasI. Chromatography separation and structural analysis showed that RasI synthesized primarily

Indexed as

Quorum SensingRalstonia solanacearumBacterial ProteinsGene Expression Regulation, BacterialTrans-ActivatorsVirulenceBacterial ProteinsTrans-Activatorsbacterial wiltcell-cell communicationpathogenesissignaling mechanism

Identifiers

PMID35876567
PMCPMC9361817
OpenAlexW4287377825

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.