Evidence map›Paper›PMID 35876534›Full record

ArticleInteractive cardiovascular and thoracic surgery2022

Aortopulmonary collaterals in single ventricle: incidence, associated factors and clinical significance.

Melvin Schmiel, Takashi Kido, Stanimir Georgiev, Melchior Burri, Paul Philipp Heinisch, Janez Vodiskar, Martina Strbad, Peter Ewert, Alfred Hager, Jürgen Hörer and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Interactive cardiovascular and thoracic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Collaterals in congenital heart disease: when and how to treat?Cardiovascular diagnosis and therapy · 2023
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Melvin SchmielDepartment of Congenital and Pediatric Heart Surgery, German Heart Center Munich, Technische Universität München, Munich, Germany.
Takashi KidoDepartment of Congenital and Pediatric Heart Surgery, German Heart Center Munich, Technische Universität München, Munich, Germany.
Stanimir GeorgievDepartment of Pediatric Cardiology and Congenital Heart Disease, German Heart Center Munich, Technical University of Munich, Munich, Germany.ORCID 0000-0002-6239-8160
Melchior BurriDepartment of Cardiovascular Surgery, German Heart Center Munich, Technische Universität München, Munich, Germany.ORCID 0000-0002-8540-7090
Paul Philipp HeinischDepartment of Congenital and Pediatric Heart Surgery, German Heart Center Munich, Technische Universität München, Munich, Germany.ORCID 0000-0003-2606-0557
Janez VodiskarDepartment of Congenital and Pediatric Heart Surgery, German Heart Center Munich, Technische Universität München, Munich, Germany.
Martina StrbadDepartment of Congenital and Pediatric Heart Surgery, German Heart Center Munich, Technische Universität München, Munich, Germany.
Peter EwertDepartment of Pediatric Cardiology and Congenital Heart Disease, German Heart Center Munich, Technical University of Munich, Munich, Germany.
Alfred HagerDepartment of Pediatric Cardiology and Congenital Heart Disease, German Heart Center Munich, Technical University of Munich, Munich, Germany.ORCID 0000-0002-2481-2017
Jürgen HörerDepartment of Congenital and Pediatric Heart Surgery, German Heart Center Munich, Technische Universität München, Munich, Germany.ORCID 0000-0002-2716-1424
Masamichi OnoDepartment of Congenital and Pediatric Heart Surgery, German Heart Center Munich, Technische Universität München, Munich, Germany.ORCID 0000-0001-5699-6394
Deutsches Herzzentrum München · DE

Funding

Förderverein des Deutschen Herzzentrums München
6 · The paper itself

Abstract

objectivesClinical significance of aortopulmonary collaterals (APCs) in patients with univentricular heart remains controversial. This study aimed to evaluate the incidence and associated factors for APCs and their influence during staged palliation.

methodsIn total, 430 patients who underwent staged palliation by bidirectional Glenn shunt and total cavopulmonary connection between 2003 and 2019 were examined. APCs were determined by angiogram. Incidence and interventions for APCs were analysed.

resultsThe most frequent diagnosis was hypoplastic left heart syndrome in 146 (34%) patients. The median age at Glenn and Fontan was 4.9 months and 2.1 years, respectively. APCs were observed in 54 (13%) patients at Glenn and in 179 (42%) at Fontan. Closure of APCs was performed before Glenn in 12 (3%) patients, at Glenn in 13 (3%), after Glenn in 8 (2%), before Fontan in 44 (10%), at Fontan in 26 (6%) and after Fontan in 52 (12%). Hypoplastic left heart syndrome (P < 0.01) was highly associated with the development of APCs before Glenn. Lower Nakata-Index and younger age at Glenn shunt were associated with the development of APCs at Fontan procedure. The presence of APCs or intervention for APCs before total cavopulmonary connection did not influence intensive care unit stay or mortality after total cavopulmonary connection.

conclusionsAPCs were most frequently observed before Fontan procedure. Hypoplastic left heart syndrome was highly associated with the development of APCs before Glenn shunt. Lower Nakata-Index and younger age at Glenn shunt were associated with APCs before Fontan procedure.

Indexed as

Fontan ProcedureHypoplastic Left Heart SyndromeUniventricular HeartHeart VentriclesHumansIncidenceInfantPalliative CarePulmonary ArteryRetrospective StudiesTreatment OutcomeAortopulmonary collateral arteriesBidirectional cavopulmonary shuntHypoplastic left heart syndromeNorwood procedureTotal cavopulmonary connection

Identifiers

PMID35876534
PMCPMC9318886
OpenAlexW4287377860

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.