Evidence map›Paper›PMID 35876507›Full record

ArticlemBio2022

Toward Uncovering the Complexities of Bacterial Interspecies Communication and Competition on the Skin.

Francis Alonzo

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Francis AlonzoDepartment of Microbiology and Immunology, College of Medicine, University of Illinois Chicago, Chicago, Illinois, USA.ORCID 0000-0001-8445-4218
University of Illinois Urbana-Champaign · US

Funding

Staphylococcus aureus Survival During Nutrient Restriction and Suppression of Host Immunity.R01AI120994 · NIAID · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Francis Alonzo · 2016 to 2026
$4.6M
Intercellular Communication and Pheromone Maturation in Gram-Positive Bacteria.R01AI153059 · NIAID · UNIVERSITY OF ILLINOIS AT CHICAGO · PI ALONZO, FRANCIS · 2020 to 2024
$1.9M
NIAID NIH HHS R01 AI120994NIAID NIH HHS R01 AI153059
6 · The paper itself

Abstract

The skin is an inhospitable environment for microbial growth and survival. Hallmarks of the skin microenvironment include low moisture, high acidity, high lipid content, and paucity of essential nutrients, which together establish an antimicrobial barrier that defends against pathogens. Yet, commensal microbes and some opportunistic pathogens call this harsh environment home. The coagulase-negative staphylococci (CoNS) comprise a major constituent of the commensal skin microbiome. Of the CoNS, Staphylococcus epidermidis and Staphylococcus hominis are two common colonizers of human skin. Although comparatively less studied than S. epidermidis, there is a growing appreciation for S. hominis as a beneficial commensal, prompting interest in understanding the mechanisms by which S. hominis interacts with other skin microbes, including those with pathogenic potential. In their recent work, M. M. Severn, M. R. Williams, A. Shahbandi, Z. L. Bunch, et al. [mBio 13(3):e00930-22, 2022, https://doi.org/10.1128/mbio.00930-22] explore quorum sensing as a mediator of S. hominis interbacterial communication that can reduce the virulence of pathogens.

Indexed as

Staphylococcal InfectionsStaphylococcal Skin InfectionsAnimal CommunicationAnimalsHumansSkinStaphylococcusStaphylococcus epidermidisAgr systemquorum sensingskin infectionskin microbiotaStaphylococcus aureusStaphylococcus hominis

Identifiers

PMID35876507
PMCPMC9426508
OpenAlexW4287378345

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.