Evidence map›Paper›PMID 35876409›Full record

ArticleJournal of the American Heart Association2022

Mortality and Cardiovascular Outcomes in Patients Presenting With Non-ST Elevation Myocardial Infarction Despite No Standard Modifiable Risk Factors: Results From the SWEDEHEART Registry.

Gemma A Figtree, Stephen T Vernon, Nermin Hadziosmanovic, Johan Sundström, Joakim Alfredsson, Stephen J Nicholls, Clara K Chow, Peter Psaltis, Helge Røsjø, Margrét Leósdóttir and 1 more

Erratum issuedAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Sex differences in survival following acute coronary syndrome with and without standard modifiable risk factors.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
    Pooled it
  2. Article
  3. The paradox of SMURF-less outcomes and its implication for diabetes.European heart journal. Quality of care & clinical outcomes · 2026
    Article
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  17. Article
  18. The hasty generalization fallacy: not all coronary artery disease is the same.International journal of cardiology. Heart & vasculature · 2024
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Gemma A FigtreeKolling Institute, Royal North Shore Hospital and University of Sydney Sydney Australia.ORCID 0000-0002-5080-6083
Stephen T VernonKolling Institute, Royal North Shore Hospital and University of Sydney Sydney Australia.ORCID 0000-0001-6262-0916
Nermin HadziosmanovicDepartment of Medical Sciences Uppsala University Uppsala Sweden.
Johan SundströmDepartment of Medical Sciences Uppsala University Uppsala Sweden.ORCID 0000-0003-2247-8454
Joakim AlfredssonFaculty of Medicine and Health Sciences Linköping University Linköping Sweden.
Stephen J NichollsMonash Cardiovascular Research Centre Victorian Heart Institute, Monash University Clayton Australia.
Clara K ChowWestmead Applied Research Centre, Faculty of Medicine and Health University of Sydney Australia.ORCID 0000-0003-4693-0038
Peter PsaltisVascular Research Centre South Australian Health and Medical Research Institute; Adelaide Medical School, University of Adelaide Australia.ORCID 0000-0003-0222-5468
Helge RøsjøAkershus University Hospital Lørenskog Norway.ORCID 0000-0003-2114-3134
Margrét LeósdóttirDepartment of Clinical Sciences, Faculty of Medicine Lund University Malmö Sweden.ORCID 0000-0003-1677-1566
Emil HagströmDepartment of Cardiology Royal North Shore Hospital Sydney Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background A significant proportion of patients with ST-segment-elevation myocardial infarction (MI) have no standard modifiable cardiovascular risk factors (SMuRFs) and have unexpected worse 30-day outcomes compared with those with SMuRFs. The aim of this article is to examine outcomes of patients with non-ST-segment-elevation MI in the absence of SMuRFs. Methods and Results Presenting features, management, and outcomes of patients with non-ST-segment-elevation MI without SmuRFs (hypertension, diabetes, hypercholesterolemia, smoking) were compared with those with SmuRFs in the Swedish MI registry SWEDEHEART (Swedish Web-System for Enhancement and Development of Evidence-Based Care in Heart Disease Evaluated According to Recommended Therapies; 2005-2018). Cox proportional hazard models were used. Out of 99 718 patients with non-ST-segment-elevation MI, 11 131 (11.2%) had no SMuRFs. Patients without SMuRFs had higher all-cause and cardiovascular mortality at 30 days (hazard ratio [HR], 1.20 [95% CI, 1.10-1.30],

Indexed as

Non-ST Elevated Myocardial InfarctionPercutaneous Coronary InterventionST Elevation Myocardial InfarctionFemaleHumansRegistriesRisk FactorsTime FactorsTreatment Outcomeatherosclerosiscoronary artery diseasemyocardial infarctionrisk factors

Identifiers

PMID35876409
PMCPMC9375489

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.