Evidence map›Paper›PMID 35876404›Full record

ArticleJournal of the American Heart Association2022

Value of Periprocedural Electrophysiology Testing During Transcatheter Aortic Valve Replacement for Risk Stratification of Patients With New-Onset Left Bundle-Branch Block.

Patrick Badertscher, Sven Knecht, Florian Spies, Chloé Auberson, Marc Salis, Raban V Jeger, Gregor Fahrni, Christoph Kaiser, Beat Schaer, Stefan Osswald and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Prognostic value of isolated PR interval prolongation after transcatheter aortic valve implantation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  2. High-density mapping of his-ventricular intervals: impact of recording site and sex-specific differences.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Article
  3. Article
  4. Article
  5. Late arrhythmic burden in patients with left bundle branch block after TAVR with the Evolut valve.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Post-transcatheter aortic valve implantation isolated PR prolongation: incidence and clinical significance.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Patrick BadertscherDepartment of Cardiology University Hospital Basel Basel Switzerland.ORCID 0000-0001-9751-0557
Sven KnechtDepartment of Cardiology University Hospital Basel Basel Switzerland.ORCID 0000-0001-7122-021X
Florian SpiesDepartment of Cardiology University Hospital Basel Basel Switzerland.ORCID 0000-0001-8974-9541
Chloé AubersonDepartment of Cardiology University Hospital Basel Basel Switzerland.
Marc SalisDepartment of Cardiology University Hospital Basel Basel Switzerland.
Raban V JegerDepartment of Cardiology University Hospital Basel Basel Switzerland.ORCID 0000-0003-1290-5491
Gregor FahrniDepartment of Cardiology University Hospital Basel Basel Switzerland.
Christoph KaiserDepartment of Cardiology University Hospital Basel Basel Switzerland.
Beat SchaerDepartment of Cardiology University Hospital Basel Basel Switzerland.
Stefan OsswaldDepartment of Cardiology University Hospital Basel Basel Switzerland.ORCID 0000-0002-9240-6731
Christian SticherlingDepartment of Cardiology University Hospital Basel Basel Switzerland.ORCID 0000-0001-8428-7050
Michael KühneDepartment of Cardiology University Hospital Basel Basel Switzerland.ORCID 0000-0002-2937-3711
University Hospital of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Despite being the most frequent complication following transcatheter aortic valve replacement (TAVR), optimal management of left bundle-branch block (LBBB) remains unknown. Electrophysiology study has been proposed for risk stratification. However, the optimal timing of electrophysiology study remains unknown. We aimed to investigate the temporal dynamics of atrioventricular conduction in patients with new-onset LBBB after TAVR by performing serial electrophysiology study and to deduce a treatment strategy. Methods and Results We assessed consecutive patients undergoing TAVR via His-ventricular interval measurement prevalve and postvalve deployment and the day after TAVR. Infranodal conduction delay was defined as a His-ventricular interval >55 milliseconds. Among 107 patients undergoing TAVR, 53 patients (50%) experienced new-onset LBBB postvalve deployment and infranodal conduction delay was noted in 24 of 53 patients intraprocedurally (45%). LBBB resolved the day after TAVR in 35 patients (66%). In patients with new-onset LBBB postvalve deployment and no infrahisian conduction delay intraprocedurally, the His-ventricular interval did not prolong in any patient to >55 milliseconds the following day. Overall, 4 patients (7.5%) with new-onset LBBB after TAVR were found to have persistent infrahisian conduction delay 24 hours after TAVR. During 30-day follow-up, 1 patient (1.1%) with new LBBB and a normal His-ventricular interval after TAVR developed new high-grade atrioventricular block. Conclusions Among patients with new-onset LBBB postvalve deployment, infrahisian conduction delay can safely be excluded intraprocedurally, suggesting that early intracardiac intraprocedural conduction studies may be of value in these patients.

Indexed as

Aortic Valve StenosisPacemaker, ArtificialTranscatheter Aortic Valve ReplacementAortic ValveArrhythmias, CardiacBundle-Branch BlockCardiac ElectrophysiologyElectrocardiographyHumansRisk AssessmentTreatment Outcomeatrioventricular conduction diseasecardiac pacemakerelectrophysiological testing

Identifiers

PMID35876404
PMCPMC9375470
OpenAlexW4287835452

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.