Evidence map›Paper›PMID 35876143›Full record

ArticleAmerican journal of respiratory and critical care medicine2023

Creatine Kinase Is Decreased in Childhood Asthma.

Stefano Guerra, Julie G Ledford, Erik Melén, Iris Lavi, Anne-Elie Carsin, Debra A Stern, Jing Zhai, Marta Vidal, Mariona Bustamante, Kenneth J Addison and 24 more

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Heterogeneity of reduced FEVRespirology (Carlton, Vic.) · 2025
    Article
  3. Article
  4. UnloCKing the Role of Creatine Kinase in Childhood Asthma.American journal of respiratory and critical care medicine · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

34 authors at 13 institutions in 5 countries.

Stefano GuerraAsthma and Airway Disease Research Center.ORCID 0000-0001-7218-3246
Julie G LedfordAsthma and Airway Disease Research Center.
Erik MelénDepartment of Clinical Science and Education and.
Iris LaviISGlobal, Barcelona, Spain.
Anne-Elie CarsinISGlobal, Barcelona, Spain.
Debra A SternAsthma and Airway Disease Research Center.
Jing ZhaiAsthma and Airway Disease Research Center.
Marta VidalISGlobal, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain.
Mariona BustamanteISGlobal, Barcelona, Spain.
Kenneth J AddisonAsthma and Airway Disease Research Center.
Renata G VallecilloDepartment of Molecular and Cellular Biology.
Dean BillheimerBIO5 Institute, and.
Gerard H KoppelmanGroningen Research Institute for Asthma and COPD, Groningen, the Netherlands.
Judith Garcia-AymerichISGlobal, Barcelona, Spain.ORCID 0000-0002-7097-4586
Nathanaël LemonnierInstitute for Advanced Biosciences, UGA-INSERM U1209-CNRS UMR5309, Site Santé, Allée des Alpes, 38700 La Tronche, France.
Montserrat FitóCardiovascular Risk and Nutrition Group and.
Carlota DobañoISGlobal, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain.
Simon Kebede MeridDepartment of Clinical Science and Education and.
Inger KullDepartment of Clinical Science and Education and.
Rosemary R C McEachanBradford Institute for Health Research, Bradford, United Kingdom.
John WrightBradford Institute for Health Research, Bradford, United Kingdom.
Leda ChatziDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.
Manolis KogevinasISGlobal, Barcelona, Spain.
Daniela PortaDepartment of Epidemiology, Lazio Regional Health Service, Rome, Italy.
Silvia NarduzziDepartment of Epidemiology, Lazio Regional Health Service, Rome, Italy.
Ferran BallesterCIBER Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain.
Ana EspluguesCIBER Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain.
Carlos ZabaletaPediatrics Service, Hospital de Zumárraga, Gipuzkoa, Spain.
Amaia IrizarCIBER Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain.
Jordi SunyerISGlobal, Barcelona, Spain.
Marilyn HalonenAsthma and Airway Disease Research Center.
Jean BousquetUniversity Hospital Montpellier, France; and.
Fernando D MartinezAsthma and Airway Disease Research Center.
Josep M AntoISGlobal, Barcelona, Spain.
Dermatology Research Center · USUniversitat Pompeu Fabra · ESBarcelona Institute for Global Health · ESCentro de Investigación en Red en Enfermedades Cardiovasculares · ESInstituto de Salud Carlos III · ESKarolinska Institutet · SEUniversitat Jaume I · ESBiogipuzkoa Health Research Institute · ESCentre National de la Recherche Scientifique · FRInserm · FRUniversity Medical Center Groningen · NLUniversity of Arizona · USUniversity of Southern California · US

Funding

SOUTHWEST ENVIRONMENTAL HEALTH SCIENCES CENTERP30ES006694 · NIEHS · UNIVERSITY OF ARIZONA · PI DEAN BILLHEIMER · 1994 to 2026
$36.7M
Early Origins of Chronic Lung Disease: Outcomes into the Fifth Decade of LifeR01HL132523 · NHLBI · UNIVERSITY OF ARIZONA · PI Stefano Guerra, Fernando D Martinez · 2016 to 2026
$15.1M
CC16 in Childhood and Resilience to Persistent Asthma into Adult Life (Supplement)R01AI135108 · NIAID · UNIVERSITY OF ARIZONA · PI Stefano Guerra · 2017 to 2026
$5.4M
Defining mechanisms of CC16 on epithelial-driven host responses to pathogensR01HL142769 · NHLBI · UNIVERSITY OF ARIZONA · PI Julie Gunnells Ledford · 2019 to 2026
$4.2M
Serum Biomarkers of COPD: a population-based prospective studyR01HL095021 · NHLBI · UNIVERSITY OF ARIZONA · PI GUERRA, STEFANO · 2009 to 2013
$2.0M
NHLBI NIH HHS R01 HL095021NHLBI NIH HHS R01 HL132523NHLBI NIH HHS R01 HL142769NIAID NIH HHS R01 AI135108NIEHS NIH HHS P30 ES006694
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AsthmaRespiratory HypersensitivityAnimalsChildCreatine KinaseCross-Sectional StudiesDisease Models, AnimalHumansLungMiceMucinsPyroglyphidaeCreatine KinaseMucinsasthmabiomarkerscreatine kinase

Identifiers

PMID35876143
PMCPMC10870915
OpenAlexW4286750379

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.