Evidence map›Paper›PMID 35875789›Full record

Trial reportNeural plasticity2022

Peripheral Repetitive Transcranial Magnetic Stimulation(rTMS) for Idiopathic Facial Nerve Palsy: A Prospective, Randomized Controlled Trial.

Zicai Liu, Dongling Xie, Xin Wen, Risheng Wang, Quan Yang, Huiyu Liu, Yuchun Shao, Tingting Liu

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Neural plasticity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07327710 (Efficacy and Safety of Non-Invasive Brain-Computer Interface Combined With Transcranial Electrical Stimulation in the Treatment of Peripheral Facial Palsy), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07327710 naenrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Efficacy and Safety of Non-Invasive Brain-Computer Interface Combined With Transcranial Electrical Stimulation in the Treatment of Peripheral Facial Palsy

TypeinterventionalSponsorNanjing Medical UniversityRan2025 to 2028Enrolled30ConditionsPeripheral Facial Palsy, Pulsed Radiofrequency, Brain-Computer Interface, Transcranial Direct Current StimulationArmsBrain-Computer Interface (BCI), Pulsed Radiofrequency (PRF), Standard Therapy
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Zicai LiuDepartment of Rehabilitation Medicine, YueBei People's Hospital, Shaoguan, 512026 Guangdong Province, China.ORCID 0000-0003-2892-0071
Dongling XieDepartment of Rehabilitation Medicine, YueBei People's Hospital, Shaoguan, 512026 Guangdong Province, China.ORCID 0000-0002-5183-3956
Xin WenSchool of Rehabilitation Medicine GanNan Medical University, Ganzhou, 341000 Jiangxi Province, China.ORCID 0000-0003-1483-0921
Risheng WangDepartment of Rehabilitation Medicine, YueBei People's Hospital, Shaoguan, 512026 Guangdong Province, China.ORCID 0000-0002-0515-4530
Quan YangDepartment of Rehabilitation Medicine, YueBei People's Hospital, Shaoguan, 512026 Guangdong Province, China.ORCID 0000-0001-8590-6984
Huiyu LiuDepartment of Rehabilitation Medicine, YueBei People's Hospital, Shaoguan, 512026 Guangdong Province, China.ORCID 0000-0002-1732-7697
Yuchun ShaoDepartment of Rehabilitation Medicine, YueBei People's Hospital, Shaoguan, 512026 Guangdong Province, China.ORCID 0000-0001-8929-5148
Tingting LiuDepartment of Rehabilitation Medicine, YueBei People's Hospital, Shaoguan, 512026 Guangdong Province, China.ORCID 0000-0001-8722-0310
Shantou University · CNGannan Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The purpose of this study was to evaluate the clinical efficacy of peripheral repetitive transcranial magnetic stimulation (rTMS) in the treatment of idiopathic facial paralysis, to explore an ideal treatment scheme for idiopathic facial paralysis, and to provide evidence for clinical rehabilitation. Methods: 65 patients with idiopathic facial nerve palsy with the first onset were recruited and randomly divided into rTMS group and control group. Both groups received conventional treatment, rTMS group received additional repetitive transcranial magnetic stimulation to the affected side once a day, 5 times a week for 2 weeks. House-Brackmann (HB) grading scale, Sunnybrook facial grading system (SFGS), and modified Portmann scale (MPS) were used to assess facial nerve function before and after treatment, and the time for patients to return to normal facial nerve function and adverse reaction (AR) was also the main observation index. Results: After a 2-week intervention, HB, SFGS, and MPS increased in both groups ( Conclusions: Repetitive transcranial magnetic stimulation is a safe and effective noninvasive method for the treatment of idiopathic facial paralysis, which can significantly accelerate the recovery of facial nerve function and provide a new treatment idea for further improving the prognosis of patients with idiopathic facial paralysis.

Indexed as

Bell PalsyTranscranial Magnetic StimulationFacial NerveHumansParalysisProspective StudiesTreatment Outcome

Identifiers

PMID35875789
PMCPMC9300274
OpenAlexW4285395594

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.