Evidence map›Paper›PMID 35875722›Full record

ReviewGene reports2022

miRNA expression in COVID-19.

Kiarash Roustai Geraylow, Romina Hemmati, Sepideh Kadkhoda, Soudeh Ghafouri-Fard

Open access · greenAbstract readReview
In one paragraph

Review in Gene reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Predicting candidate biomarkers for COVID-19 associated with leukemia in children.American journal of clinical and experimental immunology · 2024
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Cellular microRNAs target SARS-CoV-2 spike protein and restrict viral replication.American journal of physiology. Cell physiology · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Kiarash Roustai GeraylowStudent Research Committee, Semnan University of Medical Sciences, Semnan, Iran.
Romina HemmatiStudent Research Committee, Semnan University of Medical Sciences, Semnan, Iran.
Sepideh KadkhodaDepartment of Medical Genetics, Tehran University of Medical Sciences, Tehran, Iran.
Soudeh Ghafouri-FardDepartment of Medical Genetics, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Semnan University of Medical Sciences · IRShahid Beheshti University of Medical Sciences · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) is regarded as a challenge in health system. Several studies have assessed the immune-related aspect of this disorder to identify the host-related factors that affect the course of COVID-19. microRNAs (miRNAs) as potent regulators of immune responses have gained much attention in this regard. Recent studies have shown aberrant expression of miRNAs in COVID-19 in association with disease course. Differentially expressed miRNAs have been enriched in pathways related with inflammation and antiviral immune response. miRNAs have also been regarded as potential therapeutic targets in COVID-19, particularly for management of pathological consequences of COVID-19. In the current review, we summarize the data about dysregulation of miRNAs in COVID-19.

Indexed as

ACE2, Angiotensin-converting enzyme 2ARDS, Acute respiratory distress syndromeCOVID-19COVID-19, Coronavirus disease 2019hBMEC, Human brain microvascular endothelial cellsHDAC, Histone deacetylateHMVEC, Human Lung Microvascular Endothelial CellsmiRNAmiRNAs, microRNAsORF, Open reading frameROC, Receiver operating characteristicSARS-CoV-2SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2TLR, Toll-like receptorTMPRSS2, Transmembrane protease serine 2UTR, Untranslated region

Identifiers

PMID35875722
PMCPMC9288248
OpenAlexW4285679306

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.