ReviewFrontiers in molecular neuroscience2022
Depression in Adolescence and Brain-Derived Neurotrophic Factor.
Review in Frontiers in molecular neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Research hotspots and frontiers of acceptance and commitment therapy for mental disorders: a bibliometric analysis.Frontiers in psychiatry · 2025Pooled it
- Exercise and fluoxetine in Alzheimer's disease: Molecular mechanisms of synergistic and antagonistic effects (Review).International journal of molecular medicine · 2026Review
- Changes in smartphone dependence and depressive and anxiety symptoms among Chinese adolescents.BMC medicine · 2025Article
- The relationship between adherence to 24-h movement guidelines and brain-derived neurotrophic factor in adolescents: a cross-sectional study.European journal of pediatrics · 2025Article
- Correlation study of BDNF/TrkB/CREB, violence, and cognitive function in first-episode drug-naive schizophrenia patients.Frontiers in psychiatry · 2025Article
- Suicidal behaviour in adolescents with affective disorders: A study in a crisis intervention unit (CIU).PloS one · 2025Observational
- Biomarkers of Depression among Adolescent Girls: BDNF and Epigenetics.International journal of molecular sciences · 2024Article
- MiR-182-5p: A Novel Biomarker in the Treatment of Depression in CSDS-Induced Mice.The international journal of neuropsychopharmacology · 2024Article
- Associations of BDNF/BDNF-AS SNPs with Depression, Schizophrenia, and Bipolar Disorder.Journal of personalized medicine · 2023Review
- Targeting the ferroptosis crosstalk: novel alternative strategies for the treatment of major depressive disorder.General psychiatry · 2023Review
- Exosomes may be the carrier of acupuncture treatment for major depressive disorder.Frontiers in behavioral neuroscience · 2023Review
- Inflammation-activated C/EBPβ mediates high-fat diet-induced depression-like behaviors in mice.Frontiers in molecular neuroscience · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The incidence of depression among adolescents has been rapidly increasing in recent years. Environmental and genetic factors have been identified as important risk factors for adolescent depression. However, the mechanisms underlying the development of adolescent depression that are triggered by these risk factors are not well understood. Clinical and preclinical studies have focused more on adult depression, and differences in depressive symptoms between adolescents and adults make it difficult to adequately diagnose and treat adolescent depression. Brain-derived neurotrophic factor (BDNF) is known to play a critical role in the pathophysiology of many psychiatric disorders, including depression. However, there are still few studies on adolescent depression. Therefore, in this review paper, the causes and treatment of adolescent depression and the function of BDNF are investigated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.