Evidence map›Paper›PMID 35875529›Full record

ArticleFrontiers in microbiology2022

Effect of Doxycycline Use in the Early Broiler Production Cycle on the Microbiome.

Genevieve Greene, Leonard Koolman, Paul Whyte, Catherine Burgess, Helen Lynch, Aidan Coffey, Brigid Lucey, Lisa O'Connor, Declan Bolton

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Genevieve GreeneTeagasc Food Research Centre, Dublin, Ireland.
Leonard KoolmanTeagasc Food Research Centre, Dublin, Ireland.
Paul WhyteSchool of Veterinary Medicine, University College Dublin, Dublin, Ireland.
Catherine BurgessTeagasc Food Research Centre, Dublin, Ireland.
Helen LynchSchool of Veterinary Medicine, University College Dublin, Dublin, Ireland.
Aidan CoffeyDepartment of Biological Sciences, Munster Technological University, Cork, Ireland.
Brigid LuceyDepartment of Biological Sciences, Munster Technological University, Cork, Ireland.
Lisa O'ConnorFood Safety Authority of Ireland, Dublin, Ireland.
Declan BoltonTeagasc Food Research Centre, Dublin, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

16S rRNA amplicon sequencing was used to investigate changes in the broiler gastrointestinal tract (GIT) microbiota throughout the rearing period and in combination with antibiotic treatment. Thirty birds (from a commercial flock) were removed at multiple points throughout the rearing period on days 13, 27, and 33, euthanised, and their GIT aseptically removed and divided into upper (the crop, proventriculus, and the gizzard), middle (the duodenum, jejunum, and ileum) and lower (the large intestine, the caeca, and the cloaca) sections. In a separate commercial flock, on the same farm with similar husbandry practices and feed, doxycycline (100 mg/ml per kg body weight) was administered in drinking water between day 8 and 12 (inclusive) of the production cycle. Birds were removed on days, 13, 27, and 33 and GIT samples prepared as above. The contents of three merged samples from each GIT section were pooled (

Indexed as

16S rRNA amplicon sequencingantibiotic treatmentbroilersFirmicutes/Bacteroidetes ratiogastrointestinal tract microbiota

Identifiers

PMID35875529
PMCPMC9301238

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.