Evidence map›Paper›PMID 35875393›Full record

ArticleJAAD international2022

Association between excision margins and local recurrence in 1407 patients with primary in situ melanomas.

Licata Gaetano, Birra Domenico, Serigne N Lo, Tasnia Hamed, Alison J Potter, John F Thompson, Richard A Scolyer, Pascale Guitera

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JAAD international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Licata GaetanoDermatology Unit- University of Campania "Luigi Vanvitelli", Naples, Italy.
Birra DomenicoUOC Internal Medicine, Rheumatology Outpatient Unit, Azienda Ospedaliero-Universitaria San Giovanni di Dio e Ruggi D'Aragona, Salerno, Italy.
Serigne N LoMelanoma Institute Australia, The University of Sydney, Sydney, New South Wales, Australia.
Tasnia HamedMelanoma Institute Australia, The University of Sydney, Sydney, New South Wales, Australia.
Alison J PotterMelanoma Institute Australia, The University of Sydney, Sydney, New South Wales, Australia.
John F ThompsonMelanoma Institute Australia, The University of Sydney, Sydney, New South Wales, Australia.
Richard A ScolyerMelanoma Institute Australia, The University of Sydney, Sydney, New South Wales, Australia.
Pascale GuiteraMelanoma Institute Australia, The University of Sydney, Sydney, New South Wales, Australia.
University of Sydney · AURoyal Prince Alfred Hospital · AUMelanoma Institute Australia · AUOspedali Riuniti San Giovanni di Dio e Ruggi d'Aragona · ITUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Reliable evidence to guide the management of melanoma in situ (MIS) and minimize the risk of recurrence is lacking. Objective: To identify clinicopathological predictors of local recurrence (LR) in patients with MIS and evaluate long-term outcomes according to pathological excision margins. Methods: A case-control study of patients with MIS treated at a large Australian melanoma treatment center from January 2008 to December 2012 was undertaken. Clinicopathological characteristics of patients who developed LR and those who did not were compared. Results: LR developed in 34 of 1407 patients with MIS (2.5%). Median time to LR was 20 months. The primary lesion was removed with pathological margins <4 mm ( Limitations: Retrospective, single-institution study. Conclusions: Pathological margins of ≥4 mm should be considered for patients with MIS who are treated with standard surgical excision and assessed by examining serial slices taken from the formalin-fixed, paraffin-embedded specimen.

Indexed as

CCPDMA, complete circumferential peripheral and deep margin assessmentexcision marginsin situ melanomaLM, lentigo malignalocal recurrenceLR, local recurrencemelanomaMIA, Melanoma Institute AustraliaMIS, melanoma in situwider excision

Identifiers

PMID35875393
PMCPMC9305371
OpenAlexW4282972328

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.