Evidence map›Paper›PMID 35875314›Full record

ArticleCancer research communications2021

Influence of germline

Cynthia Villarreal-Garza, Ana S Ferrigno, Alejandro Aranda-Gutierrez, Paul H Frankel, Nora H Ruel, Alan Fonseca, Steven Narod, Yanin Chavarri-Guerra, Erika Sifuentes, Maria Cristina Magallanes-Hoyos and 5 more

Open access · goldAbstract read
In one paragraph

Article in Cancer research communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pathogenic variants inJournal of medicine and life · 2025
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 3 countries.

Cynthia Villarreal-GarzaBreast Cancer Center, Hospital Zambrano Hellion TecSalud, Tecnologico de Monterrey, San Pedro Garza Garcia, Nuevo Leon, Mexico.
Ana S FerrignoBreast Cancer Center, Hospital Zambrano Hellion TecSalud, Tecnologico de Monterrey, San Pedro Garza Garcia, Nuevo Leon, Mexico.
Alejandro Aranda-GutierrezInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Paul H FrankelCity of Hope Cancer Center, Duarte, California, United States of America.
Nora H RuelCity of Hope Cancer Center, Duarte, California, United States of America.
Alan FonsecaInstituto Nacional de Cancerología, Mexico City, Mexico.
Steven NarodWomen's College Research Institute, University of Toronto, Toronto.
Yanin Chavarri-GuerraInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Erika SifuentesInstituto Nacional de Cancerología, Mexico City, Mexico.
Maria Cristina Magallanes-HoyosInstituto Nacional de Cancerología, Mexico City, Mexico.
Josef HerzogCity of Hope Cancer Center, Duarte, California, United States of America.
Danielle CastilloCity of Hope Cancer Center, Duarte, California, United States of America.
Rosa M Alvarez-GomezInstituto Nacional de Cancerología, Mexico City, Mexico.
Alejandro Mohar-BetancourtInstituto Nacional de Cancerología, Mexico City, Mexico.
Jeffrey N WeitzelLatin American School of Oncology, Sierra Madre, California, United States of America.
Instituto Nacional de Cancerología · MXCity Of Hope National Medical Center · USHospital Zambrano Hellion · MXInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán · MXSierra Engineering (United States) · USWomen's College Hospital · CA

Funding

Transgenic Mouse FacilityP30CA033572 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI XIWEI WU · 1985 to 2026
$86.3M
Clinical Cancer Genetics Community Network: A Sustainable Research PartnershipRC4CA153828 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI WEITZEL, JEFFREY N · 2010 to 2010
$1.0M
Hereditary Breast Cancer and Novel Hispanic BRCA MutationsR03CA139588 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI WEITZEL, JEFFREY N · 2009 to 2009
$83k
NCI NIH HHS P30 CA033572NCI NIH HHS R03 CA139588NCI NIH HHS RC4 CA153828
6 · The paper itself

Abstract

The presence of

Indexed as

Triple Negative Breast NeoplasmsFemaleGenes, BRCA1Genes, BRCA2HeterozygoteHumansMutationBRCAbreast cancergermline mutationpremenopausalsurvivaltriple-negativeyoung women

Identifiers

PMID35875314
PMCPMC9307147
OpenAlexW4200247581

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.