Evidence map›Paper›PMID 35875248›Full record

ReviewEmergency medicine international2022

Preparation of PCL Electrospun Fibers Loaded with Cisplatin and Their Potential Application for the Treatment of Prostate Cancer.

Hilla Mills, Ronald Acquah, Nova Tang, Luke Cheung, Susanne Klenk, Ronald Glassen, Magali Pirson, Alain Albert, Duong Trinh Hoang, Thang Nguyen Van

RetractedOpen access · goldAbstract readReviewRetracted Publication
In one paragraph

Review in Emergency medicine international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. FePharmaceutics · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Hilla MillsDepartment of Medical Science, University for Development, Accra, Ghana.ORCID https://orcid.org/0000-0003-2032-9279
Ronald AcquahDepartment of Medical Science, University for Development, Accra, Ghana.
Nova TangRD Lab, The Hospital Institute for Hebal Research, 50200 Toluca, Mexico, Mexico.
Luke CheungRD Lab, The Hospital Institute for Hebal Research, 50200 Toluca, Mexico, Mexico.ORCID https://orcid.org/0000-0003-2723-5910
Susanne KlenkResearch Institution of Clinical Biomedicine, Hospital University Medical Centre, 89000 Ulm, Germany.
Ronald GlassenResearch Institution of Clinical Biomedicine, Hospital University Medical Centre, 89000 Ulm, Germany.ORCID https://orcid.org/0000-0003-3195-5718
Magali PirsonIndustrial Research Group, International College of Science and Technology, Route de Lennik 800, CP 590, 1070 Brussels, Belgium.
Alain AlbertIndustrial Research Group, International College of Science and Technology, Route de Lennik 800, CP 590, 1070 Brussels, Belgium.ORCID https://orcid.org/0000-0003-1012-7331
Duong Trinh HoangClinical Analysis Lab, Center of Bio-Medicine, Hanoi, Vietnam.
Thang Nguyen VanClinical Analysis Lab, Center of Bio-Medicine, Hanoi, Vietnam.ORCID https://orcid.org/0000-0003-1628-0011
University for Development Studies · GHUniversity Hospital Ulm · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer is a global fatal type of cancer. It is a type of cancer that affect men. Signs and symptoms of the disease include blood in the urine, pain when one micturates, and difficulties in penis erection. Cisplatin chemotherapy is a principal treatment normally given to the prostate cancer patients. Nonetheless, on its own, cisplatin loses efficacy once administered due to liver pass effects and other biochemical attacks. In this paper, we looked at preparation of PCL nanoparticles loaded with cisplatin and their potential for the treatment of prostate cancer. PCL nanoparticles protect cisplatin from biochemical attack, thus increasing drug efficacy. Incorporation of P-glycoprotein inhibitors in PCL nanoparticles (NPs) loaded with cisplatin could improve prostate cancer treatment even more.

Identifiers

PMID35875248
PMCPMC9307411
OpenAlexW4285591186

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.